Department of Radiology, The First Affiliated Hospital of Dalian Medical University, 222 Zhongshan Road, Xigang District, Dalian, 116011, China.
Jpn J Radiol. 2023 Oct;41(10):1084-1093. doi: 10.1007/s11604-023-01433-y. Epub 2023 Apr 17.
Cardiac magnetic resonance (CMR) feature tracking (FT) is more widely used in the measurement of left atrial (LA) strain and strain rate (SR). However, in recent years, researchers have attempted to improve the low temporal resolution of CMR-FT to better capture the subtle deformations of the myocardium. The technique of compressed sensing (CS) has been applied clinically, reducing scan time while increasing temporal resolution. The purpose of this study was to explore the effect of the increased temporal resolution of CS cine sequences on the analysis of LA longitudinal strain and SR.
Twenty-nine healthy subjects were included in the study. They underwent CMR with a reference steady-state free precession cine sequence of conventional temporal resolution (standard SSFP sequence), a cine sequence of higher temporal resolution (HT sequence), and an HT cine sequence with CS (CS HT sequence) (temporal resolution: 22.1-44.3/24.9-47.1 ms, 11.1-19.4 ms, and 8.3-19.4 ms, respectively). The standard SSFP sequence, HT sequence, and CS HT sequence were acquired in all subjects during the same scanning session. LA longitudinal strain and SR, reflecting LA reservoir, conduit, and contraction booster-pump function, were measured by CMR-FT and compared among the three sequences.
The measurements of LASR reservoir, conduit, and booster-pump were significantly higher on the HT and CS HT sequences than on the standard SSFP sequence. The standard SSFP sequence was correlated significantly with the HT and CS HT sequences in terms of LA strain and SR analysis, respectively. The LA strain and SR measurements also showed excellent agreement between the HT and CS HT sequences.
Higher temporal resolution led to significantly higher measured LASR values in CMR-FT. Furthermore, the addition of CS reduced scan time and did not affect LA longitudinal strain or SR analysis.
心脏磁共振（CMR）特征追踪（FT）在测量左心房（LA）应变和应变率（SR）方面应用更为广泛。然而，近年来，研究人员试图提高 CMR-FT 的时间分辨率，以更好地捕捉心肌的细微变形。压缩感知（CS）技术已在临床上应用，在减少扫描时间的同时提高了时间分辨率。本研究旨在探讨 CS 电影序列时间分辨率的提高对 LA 纵向应变和 SR 分析的影响。
研究纳入 29 名健康受试者。他们接受了 CMR 检查，包括常规时间分辨率的参考稳态自由进动电影序列（标准 SSFP 序列）、时间分辨率更高的电影序列（HT 序列）和 CS 增强的 HT 电影序列（CS HT 序列）（时间分辨率分别为 22.1-44.3/24.9-47.1ms、11.1-19.4ms 和 8.3-19.4ms）。在同一扫描过程中，所有受试者均采集了标准 SSFP 序列、HT 序列和 CS HT 序列。通过 CMR-FT 测量 LA 纵向应变和 SR，比较三种序列之间的差异。
HT 序列和 CS HT 序列测量的 LA 应变和 SR 明显高于标准 SSFP 序列。标准 SSFP 序列与 HT 序列和 CS HT 序列在 LA 应变和 SR 分析方面均具有显著相关性。HT 序列和 CS HT 序列之间的 LA 应变和 SR 测量也具有很好的一致性。
更高的时间分辨率导致 CMR-FT 测量的 LASR 值显著升高。此外，CS 的加入缩短了扫描时间，且不影响 LA 纵向应变或 SR 分析。
