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病例报告:免疫功能正常者在注射曲安奈德后发生脓肿分枝杆菌感染所致的多发性头皮脓肿

Case Report: Multiple Scalp Abscesses due to Mycobacterium abscessus Infection Following Triamcinolone Injection in an Immunocompetent Person.

作者信息

Mohanty Monalisa, Mishra Baijayantimala, Sirka Chandra Sekhar, Mohapatra Prasanta Raghab

机构信息

Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Department of Dermatology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

出版信息

Am J Trop Med Hyg. 2022 Aug 8;107(3):592-4. doi: 10.4269/ajtmh.22-0126.

Abstract

Mycobacterium abscessus complex is a group of nontuberculous mycobacteria (NTM). The NTM may involve skin, soft tissue, and other organs like the eye and central nervous system. Clinically may mimic multidrug resistance. Here, we present a case of a 29-year man with a history of multiple scalp swellings with mild symptoms. He had undergone multiple triamcinolone acetonide injections on his scalp to stop hair fall and baldness 2 months prior. As there was a history of injections on the scalp and lesions associated with minimal symptoms, we suspected the possibility of NTM and fungal infections. As a part of treatment and obtaining a sample for investigation, lesions were aspirated with a needle. The swellings contained gelatinous material, which was sent for microscopic examination, and revealed the presence of acid-fast bacilli (AFB). Xpert MTB/RIF assay was negative for mycobacteria (MTB complex), but culture revealed NTM, identified as M. abscessus complex by line probe assay. Based on the diagnosis, the patient was treated with an injection of amikacin, moxifloxacin, and azithromycin. The lesions improved. The patient has completed over a year of follow-up with no recurrence noted. Mycobacterium abscessus, a rapidly growing NTM, has been occasionally reported to cause cutaneous soft tissue infection when injected with nonsterile medicine or needles. Therefore, a high index of suspicion for NTM infection is warranted in patients with cutaneous scalp abscess following scalp injections for hair loss.

摘要

脓肿分枝杆菌复合体是一组非结核分枝杆菌(NTM)。NTM可累及皮肤、软组织以及眼和中枢神经系统等其他器官。临床上可能类似耐多药情况。在此,我们报告一例29岁男性病例,其有多次头皮肿胀病史,症状较轻。2个月前他曾在头皮上多次注射曲安奈德以防止脱发和秃顶。由于有头皮注射史且病变症状轻微,我们怀疑有NTM和真菌感染的可能性。作为治疗的一部分并获取样本进行检查,用针抽取了病变组织。肿胀部位含有胶冻状物质,将其送去做显微镜检查,结果显示存在抗酸杆菌(AFB)。Xpert MTB/RIF检测对分枝杆菌(MTB复合体)呈阴性,但培养显示为NTM,经线性探针检测鉴定为脓肿分枝杆菌复合体。根据诊断,该患者接受了阿米卡星、莫西沙星和阿奇霉素注射治疗。病变有所改善。患者已完成一年多的随访,未发现复发。脓肿分枝杆菌是一种快速生长的NTM,偶尔有报道称在注射非无菌药物或针头时会引起皮肤软组织感染。因此,对于因脱发在头皮注射后出现头皮皮肤脓肿的患者,有必要高度怀疑NTM感染。

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本文引用的文献

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Treatment of Mycobacterium abscessus Complex.脓肿分枝杆菌复合体的治疗。
Semin Respir Crit Care Med. 2018 Jun;39(3):362-376. doi: 10.1055/s-0038-1651494. Epub 2018 Aug 2.
4
Mycobacterium abscessus Complex Infections in Humans.人类脓肿分枝杆菌复合群感染
Emerg Infect Dis. 2015 Sep;21(9):1638-46. doi: 10.3201/2109.141634.
5
Environmental sources of nontuberculous mycobacteria.环境中非结核分枝杆菌的来源。
Clin Chest Med. 2015 Mar;36(1):35-41. doi: 10.1016/j.ccm.2014.10.003. Epub 2014 Nov 6.

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