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三级护理大学医疗中心急诊科急性腹泻的管理。

Management of acute diarrhea in the emergency department of a tertiary care university medical center.

机构信息

Division of Gastroenterology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

J Int Med Res. 2022 Aug;50(8):3000605221115385. doi: 10.1177/03000605221115385.

Abstract

OBJECTIVES

To examine the management of acute diarrhea in the emergency department (ED) of a large university medical center.

METHODS

Retrospective cross-sectional study over a 10-month period of adult patients (age ≥18 years) presenting to the ED with acute diarrhea.

RESULTS

Data for 780 patients were reviewed; 101 met the exclusion criteria. Of the 679 patients with acute community-acquired diarrhea, 582 (85.7%) were discharged home and constituted the study cohort of mostly healthy adults (mean age: 32.5 ± 14.5 years). The rate of antibiotic prescription at discharge was 26%. Inappropriate use of antibiotics occurred in 28% of the patients. The presence of fever (odds ratio (OR) = 3.52), leukocytosis (OR = 1.72), and older age (OR = 1.16) were predictors of antibiotic prescription. Patients with dehydration, comorbidities, or bloody diarrhea were more likely to receive antibiotics. Microbiological studies and cross-sectional imaging were ordered in 12.4% and 11.7% of the patients, respectively, but provided very low yield (<10% for both) resulting in significantly higher visit charges. Inappropriately prescribed antibiotics at discharge resulted in higher charges in the ED compared with no antibiotic prescription.

CONCLUSION

Acute diarrhea management in our ED is suboptimal and does not adhere to practice guidelines, resulting in unnecessary antibiotic prescriptions, investigations, and cost.

摘要

目的

研究大型大学医学中心急诊科(ED)急性腹泻的管理情况。

方法

对 10 个月内因急性腹泻就诊于 ED 的成年患者(年龄≥18 岁)进行回顾性横断面研究。

结果

共回顾了 780 例患者的数据,其中 101 例不符合排除标准。在 679 例急性社区获得性腹泻患者中,582 例(85.7%)被送回家中,构成了以健康成年人为主的研究队列(平均年龄:32.5±14.5 岁)。出院时开具抗生素的比例为 26%。抗生素的使用存在不恰当情况,发生率为 28%。发热(比值比(OR)=3.52)、白细胞增多(OR=1.72)和年龄较大(OR=1.16)是开具抗生素的预测因素。有脱水、合并症或血性腹泻的患者更可能接受抗生素治疗。分别有 12.4%和 11.7%的患者进行了微生物学研究和横断面影像学检查,但结果阳性率非常低(两者均<10%),导致就诊费用显著增加。出院时开具不适当的抗生素与 ED 就诊费用较高有关。

结论

我们 ED 对急性腹泻的管理并不理想,不符合实践指南,导致不必要的抗生素处方、检查和费用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff99/9373141/f630c1f45b79/10.1177_03000605221115385-fig1.jpg

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