Maringhini A, Thiruvengadam R, Melton L J, Hench V S, Zinsmeister A R, DiMagno E P
Cancer. 1987 Jul 15;60(2):245-7. doi: 10.1002/1097-0142(19870715)60:2<245::aid-cncr2820600222>3.0.co;2-s.
To estimate the risk of pancreatic cancer after gastric surgery for benign disease, we followed all 336 residents of Olmsted County, Minnesota, who had surgical treatment for benign peptic ulcer disease during the years 1935 to 1959. These patients were followed for 6549 person-years of observation. Pancreatic cancer developed in only one patient although 1.6 primary pancreatic cancers were expected (relative risk 0.64; 95% confidence interval, 0.02 to 3.53) based on pancreatic cancer incidence rates for the general population of Olmsted County. We conclude that in our study the incidence of pancreatic cancer is not significantly increased after gastric surgery.
为评估良性疾病胃手术后患胰腺癌的风险，我们对明尼苏达州奥尔姆斯特德县的所有336名居民进行了随访，这些居民在1935年至1959年期间因良性消化性溃疡疾病接受了手术治疗。这些患者接受了6549人年的观察。尽管根据奥尔姆斯特德县普通人群的胰腺癌发病率预计会有1.6例原发性胰腺癌，但只有1例患者患了胰腺癌（相对风险0.64；95%置信区间，0.02至3.53）。我们得出结论，在我们的研究中，胃手术后胰腺癌的发病率没有显著增加。
