• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Matrix Metalloproteinase-12 Supports Pulmonary B Cell Follicle Formation and Local Antibody Responses During Asthma.

作者信息

Pyle Chloe J, Patel Dhiren F, Peiró Teresa, Joulia Régis, Grabiec Aleksander M, Hussell Tracy, Tavernier Gael, Simpson Angela, Pease James, Harker James A, Lloyd Clare M, Snelgrove Robert J

机构信息

Imperial College London London, United Kingdom.

Universidad de Valencia Valencia, Spain.

出版信息

Am J Respir Crit Care Med. 2022 Dec 1;206(11):1424-1428. doi: 10.1164/rccm.202109-2082LE.

DOI:10.1164/rccm.202109-2082LE
PMID:35944138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9746859/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dc9/9746859/f6f9046c1654/rccm.202109-2082LEf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dc9/9746859/4f264e8b3930/rccm.202109-2082LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dc9/9746859/f6f9046c1654/rccm.202109-2082LEf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dc9/9746859/4f264e8b3930/rccm.202109-2082LEf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dc9/9746859/f6f9046c1654/rccm.202109-2082LEf2.jpg

相似文献

1
Matrix Metalloproteinase-12 Supports Pulmonary B Cell Follicle Formation and Local Antibody Responses During Asthma.基质金属蛋白酶-12在哮喘期间支持肺B细胞滤泡形成和局部抗体反应。
Am J Respir Crit Care Med. 2022 Dec 1;206(11):1424-1428. doi: 10.1164/rccm.202109-2082LE.
2
Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity.慢性阻塞性肺疾病和哮喘患者的痰液基质金属蛋白酶-12：与疾病严重程度的关系。
J Allergy Clin Immunol. 2012 Mar;129(3):655-663.e8. doi: 10.1016/j.jaci.2011.12.996. Epub 2012 Feb 2.
3
Matrix metalloproteinase 12, asthma, and COPD.基质金属蛋白酶12、哮喘与慢性阻塞性肺疾病
N Engl J Med. 2009 Dec 31;361(27):2664-5. doi: 10.1056/NEJMe0910626. Epub 2009 Dec 16.
4
MMP12, lung function, and COPD in high-risk populations.高危人群中的基质金属蛋白酶12、肺功能与慢性阻塞性肺疾病
N Engl J Med. 2010 Apr 1;362(13):1241; author reply 1242. doi: 10.1056/NEJMc1000959.
5
Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults.基质金属蛋白酶-12 是儿童和青年哮喘的治疗靶点。
J Allergy Clin Immunol. 2010 Jul;126(1):70-6.e16. doi: 10.1016/j.jaci.2010.03.027. Epub 2010 May 23.
6
Increase in the expression of matrix metalloproteinase-12 in the airways of rats with allergic bronchial asthma.过敏性支气管哮喘大鼠气道中基质金属蛋白酶-12表达增加。
Biol Pharm Bull. 2007 Feb;30(2):318-23. doi: 10.1248/bpb.30.318.
7
What genes tell us about the pathogenesis of asthma and chronic obstructive pulmonary disease.基因告诉我们哮喘和慢性阻塞性肺疾病的发病机制。
Am J Respir Crit Care Med. 2010 Jun 1;181(11):1170-3. doi: 10.1164/rccm.201001-0069PP. Epub 2010 Feb 4.
8
MMP12, lung function, and COPD in high-risk populations.基质金属蛋白酶12、肺功能与高危人群中的慢性阻塞性肺疾病
N Engl J Med. 2010 Apr 1;362(13):1241; author reply 1242.
9
Matrix metalloproteinase 12 silencing: a therapeutic approach to treat pathological lung tissue remodeling?基质金属蛋白酶12沉默：一种治疗病理性肺组织重塑的方法？
Pulm Pharmacol Ther. 2009 Aug;22(4):267-78. doi: 10.1016/j.pupt.2009.03.001. Epub 2009 Mar 25.
10
Roger S. Mitchell lecture. Uses of expression microarrays in studies of pulmonary fibrosis, asthma, acute lung injury, and emphysema.
Chest. 2002 Mar;121(3 Suppl):21S-25S. doi: 10.1378/chest.121.3_suppl.21s-a.

引用本文的文献

1
Exploring transcriptomic mechanisms underlying pulmonary adaptation to diverse environments in Indian rams.探索印度公羊适应不同环境的转录组学机制。
Mol Biol Rep. 2024 Nov 1;51(1):1111. doi: 10.1007/s11033-024-10067-w.
2
A human model of asthma exacerbation reveals transcriptional programs and cell circuits specific to allergic asthma.哮喘加重的人类模型揭示了特应性哮喘特有的转录程序和细胞回路。
Sci Immunol. 2023 May 12;8(83):eabq6352. doi: 10.1126/sciimmunol.abq6352. Epub 2023 May 5.

本文引用的文献

1
B cell zone reticular cell microenvironments shape CXCL13 gradient formation.B 细胞区网状细胞微环境塑造 CXCL13 浓度梯度的形成。
Nat Commun. 2020 Jul 22;11(1):3677. doi: 10.1038/s41467-020-17135-2.
2
An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness.细胞外基质片段驱动上皮重塑和气道高反应性。
Sci Transl Med. 2018 Aug 22;10(455). doi: 10.1126/scitranslmed.aaq0693.
3
Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains.
CXCL13 与硫酸乙酰肝素结合的结构表明，糖胺聚糖结合位点和细胞信号转导依赖于不同的结构域。
Open Biol. 2017 Oct;7(10). doi: 10.1098/rsob.170133.
4
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs.IL-17 诱导的 CXCL12 招募 B 细胞并在没有分化的 FDC 的情况下诱导 BALT 中的滤泡形成。
J Exp Med. 2014 Apr 7;211(4):643-51. doi: 10.1084/jem.20131737. Epub 2014 Mar 24.
5
Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity.慢性阻塞性肺疾病和哮喘患者的痰液基质金属蛋白酶-12：与疾病严重程度的关系。
J Allergy Clin Immunol. 2012 Mar;129(3):655-663.e8. doi: 10.1016/j.jaci.2011.12.996. Epub 2012 Feb 2.
6
Role of CXCL13 in asthma: novel therapeutic target.CXCL13 在哮喘中的作用：新的治疗靶点。
Chest. 2012 Apr;141(4):886-894. doi: 10.1378/chest.11-0633. Epub 2011 Oct 20.
7
Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx.巨噬细胞特异性金属弹性蛋白酶（MMP-12）可截断并使ELR+CXC趋化因子失活，还能生成CCL2、-7、-8和-13拮抗剂：巨噬细胞在终止多形核白细胞流入中的潜在作用。
Blood. 2008 Oct 15;112(8):3455-64. doi: 10.1182/blood-2007-12-129080. Epub 2008 Jul 25.
8
Extracellular matrix components and regulators in the airway smooth muscle in asthma.哮喘患者气道平滑肌中的细胞外基质成分及调节因子
Eur Respir J. 2008 Jul;32(1):61-9. doi: 10.1183/09031936.00147807. Epub 2008 Mar 5.
9
Mucosal immunity in asthma and chronic obstructive pulmonary disease: a role for immunoglobulin A?哮喘和慢性阻塞性肺疾病中的黏膜免疫：免疫球蛋白A的作用？
Proc Am Thorac Soc. 2004;1(2):125-35. doi: 10.1513/pats.2306032.
10
Aggregations of lymphoid cells in the airways of nonsmokers, smokers, and subjects with asthma.非吸烟者、吸烟者和哮喘患者气道中淋巴细胞的聚集。
Am J Respir Crit Care Med. 2004 Mar 15;169(6):712-8. doi: 10.1164/rccm.200308-1167OC. Epub 2004 Jan 7.