Suppr超能文献

眼眶肿瘤及肿瘤样病变:一项基于医院的研究。

Orbital Tumors and Tumor like Lesions: A Hospital Based Study.

机构信息

Biratnagar Eye Hospital, Abhibadan marg, Rani, Biratnagar, Nepal.

出版信息

J Nepal Health Res Counc. 2022 Jun 2;20(1):26-32. doi: 10.33314/jnhrc.v20i01.3727.

Abstract

BACKGROUND

Orbital tumors have rare incidence, still they play a significant role in terms of morbidity and mortality. Orbital tumors may be primary, secondary or metastatic. These consist of benign and malignant lesions with extreme variations in pediatric and adult groups. These lesions can have acute or chronic onset, slow to rapid progression with or without bony destructions leading to vision loss, deformity and sometimes death.

METHODS

This retrospective cross-sectional study was carried out in the Department of Ophthalmic Pathology and Laboratory Medicine in Biratnagar Eye Hospital. Fifty-one patients who underwent histopathological evaluation for their orbital lesions from June 2018 to December 2019 were included in the study.

RESULTS

Orbital tumor and tumor like lesions comprised 27 cases (52.94%) in adults and 24 (47.06%) in paediatrics. Histopathologically, the most common pediatric benign tumor was dermoid cyst and malignant was secondary to orbital extension of retinoblastoma. Also, the most common adult benign orbital tumor was cavernous hemangioma and malignant was non Hodgkins lymphoma. The clinico-pathological accuracy for diagnosis was 68.63%. Association between age groups and nature of orbital lesions and between clinical and histopathological diagnosis was found to be statistically significant (p<0.05).

CONCLUSIONS

Orbital tumors and tumor like lesions are uncommonly encountered. These masses showed significant variation in incidence in children versus adults. Combined efforts by different specialties help in early and prompt management of the orbital tumors.

摘要

背景

眼眶肿瘤发病率较低,但在发病率和死亡率方面仍具有重要意义。眼眶肿瘤可为原发性、继发性或转移性。这些肿瘤包括良性和恶性病变,在儿科和成人组中差异极大。这些病变可急性或慢性起病,进展缓慢或迅速,伴有或不伴有骨破坏,导致视力丧失、畸形,有时甚至死亡。

方法

本回顾性横断面研究在比拉德讷格尔眼科医院眼科病理与实验室医学系进行。纳入 2018 年 6 月至 2019 年 12 月期间因眼眶病变接受组织病理学评估的 51 例患者。

结果

成人眼眶肿瘤及肿瘤样病变 27 例(52.94%),儿科 24 例(47.06%)。组织病理学上,儿童最常见的良性肿瘤是皮样囊肿,恶性肿瘤继发于视网膜母细胞瘤的眼眶延伸;而成人最常见的良性眼眶肿瘤是海绵状血管瘤,恶性肿瘤是非霍奇金淋巴瘤。临床病理诊断的准确性为 68.63%。年龄组与眼眶病变性质之间以及临床与组织病理学诊断之间的关联具有统计学意义(p<0.05)。

结论

眼眶肿瘤及肿瘤样病变并不常见。这些肿块在儿童和成人中的发病率有显著差异。不同专业的共同努力有助于早期和及时管理眼眶肿瘤。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验