Wang L Y, Shao A, Meng S K, Huang F B, Bai H X, Gao T, Yao K, Ye J
Eye Center, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
Shaanxi Eye Hospital, Xi'an People'sHospital (Xi'an Fourth Hospital), Affiliated People's Hospital of Northwest University, Xi'an 710004, China.
Zhonghua Yan Ke Za Zhi. 2023 Jan 11;59(1):20-25. doi: 10.3760/cma.j.cn112142-20220802-00373.
To investigate the histopathological classification of orbital space-occupying lesions. This is a retrospective case series study. The clinical and pathological data of 1 913 tissue specimens from 1 913 patients with space-occupying lesions of the orbit which were examined in the Second Affiliated Hospital, Zhejiang University School of Medicine from January 2000 to December 2021 were collected. The mass lesions were classified based on histogenesis, pathological nature and age. There were 913 males (47.7%) and 1 000 females (52.3%). The lesions were benign in 1 489 patients (77.8%) and malignant in 424 patients (22.2%). Based on histogenesis, there were 521 vasculogenic lesions (27.2%), which rancked first, 407 cystoid lesions (21.3%), 277 lymphoproliferative lesions (14.5%), 182 lacrimal gland lesions (9.5%) and 121 inflammatory lesions (6.3%). By pathological nature, there were 1 489 benign lesions, including cavernous hemangioma (275, 14.4%), dermoid cyst (225, 11.8%), other hemangiomas (199, 10.4%), epidermoid cyst (136, 7.1%) and benign mixed tumor of the lacrimal gland (134, 7.0%), and 257 malignant lesions, including lymphoma (210, 11.0%) and sebaceous gland carcinoma (47, 2.5%). The age of all patients ranged from 0 to 90 years, while 247 lesions (12.9%) occurred in patients aged 0 to18 years, 1 270 lesions (66.4%) in patients aged 19 to 59 years, and 396 lesions (20.7%) in patients aged 60 to 90 years. In 22 years, almost 2/3 benign orbital lesions in the Second Affiliated Hospital, Zhejiang University School of Medicine occurred in young and middle-aged patients, and males were fewer than females. The most common benign orbital tumors was cavernous hemangioma, followed by dermoid cyst and epidermoid cyst. And the most common malignant orbital tumor was lymphoma, which occurred more frequently in older patients.
探讨眼眶占位性病变的组织病理学分类。这是一项回顾性病例系列研究。收集了2000年1月至2021年12月在浙江大学医学院附属第二医院检查的1913例眼眶占位性病变患者的1913份组织标本的临床和病理资料。根据组织发生、病理性质和年龄对肿块病变进行分类。男性913例（47.7%），女性1000例（52.3%）。病变为良性者1489例（77.8%），恶性者424例（22.2%）。基于组织发生，血管源性病变521例（27.2%），居首位，囊样病变407例（21.3%），淋巴增生性病变277例（14.5%），泪腺病变182例（9.5%），炎性病变121例（6.3%）。按病理性质，良性病变1489例，包括海绵状血管瘤（275例，14.4%）、皮样囊肿（225例，11.8%）、其他血管瘤（199例，10.4%）、表皮样囊肿（136例，7.1%）和泪腺良性混合瘤（134例，7.0%）；恶性病变257例，包括淋巴瘤（210例，11.0%）和皮脂腺癌（47例，2.5%）。所有患者年龄范围为0至90岁，其中0至18岁患者有247例病变（12.9%），19至59岁患者有1270例病变（66.4%），60至90岁患者有396例病变（20.7%）。22年间，浙江大学医学院附属第二医院近2/3的眼眶良性病变发生在中青年患者中，男性少于女性。最常见的眼眶良性肿瘤是海绵状血管瘤，其次是皮样囊肿和表皮样囊肿。最常见的眼眶恶性肿瘤是淋巴瘤，在老年患者中更常见。
