Kenneally Ryan, Lawrence Quentin, Brydon Ella, Wan Kenneth H, Mao Jian-Hua, Verma Subhash C, Khazaieli Amir, Celniker Susan E, Snijders Antoine M
Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA, 94720, USA.
Department of Microbiology and Immunology, University of Nevada, Reno School of Medicine, 1664 N Virginia Street, Reno, NV, 89557, USA.
Med Microecol. 2022 Dec;14:100059. doi: 10.1016/j.medmic.2022.100059. Epub 2022 Aug 5.
SARS-CoV-2 spread rapidly, causing millions of deaths across the globe. As a result, demand for medical supplies and personal protective equipment (PPE) surged and supplies dwindled. Separate entirely, hospital-acquired infections have become commonplace and challenging to treat. To explore the potential of novel sterilization techniques, this study evaluated the disinfection efficacy of Fathhome's ozone-based, dry-sanitizing device by dose and time response. Inactivation of human pathogens was tested on non-porous (plastic) surfaces. 95.42-100% inactivation was observed across all types of vegetative microorganisms and 27.36% inactivation of bacterial endospores tested, with no residual ozone detectable after completion. These results strongly support the hypothesis that Fathhome's commercial implementation of gas-based disinfection is suitable for rapid decontamination of a wide variety of pathogens on PPE and other industrially relevant materials.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）迅速传播，在全球范围内造成数百万人死亡。因此，对医疗用品和个人防护装备（PPE）的需求激增，而供应却减少了。完全独立来看，医院获得性感染已变得司空见惯且难以治疗。为了探索新型消毒技术的潜力，本研究通过剂量和时间响应评估了法净（Fathhome）基于臭氧的干式消毒设备的消毒效果。在无孔（塑料）表面测试了对人类病原体的灭活情况。在所有类型的营养微生物中观察到95.42% - 100%的灭活率，对测试的细菌芽孢的灭活率为27.36%，完成后未检测到残留臭氧。这些结果有力地支持了以下假设：法净基于气体的消毒商业化应用适用于对PPE和其他工业相关材料上的多种病原体进行快速去污。
