Department of Cardiology, Erzurum Training and Research Hospital, Erzurum, Turkey.
Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.
Anatol J Cardiol. 2022 Sep;26(9):725-732. doi: 10.5152/AnatolJCardiol.2022.1677.
Intermittent malfunction is a rare but potentially serious complication of prosthetic heart valve replacement. This study aimed to describe the clinical features and etiologic causes of patients with intermittent mechanical prosthetic heart valve dysfunction.
Between 2010 and 2021, 16 patients who were evaluated in the echocardiography laboratory of Koşuyolu Training and Research Hospital with the diagnosis of intermittent malfunction of prosthetic valves were included in the study.
The evaluated patients consisted of 12 bi-leaflet mitral valve replacements and 2 mono-leaflet mitral valve replacements. The underlying causes of intermittent malfunction were classified as follows: residual chord (n=4), obstructive thrombus (n=2), non-obstructive thrombus (n=2), vegetation (n=2), pannus and obstructive thrombus coexistence (n=1), and solely pannus (n=1). One of the patients with mono-leaflet mitral valve replacements had pannus and obstructive thrombus. In the other patient with mono-leaflet mitral valve replacement, a stuck valve was observed in 1 of 12 beats secondary to arrhythmia. There were also 2 patients with aortic valve replacements. One patient had moderate aortic regurgitation due to prominent calcification and the other had moderate obstruction due to pannus. In the patient with pannus, a stuck leaflet was observed in 1 of 6 beats and moderate aortic regurgitation arose in 1 of 2 beats in the patient with calcification.
The intermittent stuck valve may have catastrophic outcomes. When making a treatment decision in these patients, assessing the degree of regurgitation or stenosis is essential. In particular, the frequency of entrapment should be taken into consideration when deciding the optimal therapy for intermittent prosthetic heart valve dysfunction.
人工心脏瓣膜置换术后间歇性故障是一种罕见但潜在严重的并发症。本研究旨在描述间歇性机械人工心脏瓣膜功能障碍患者的临床特征和病因。
2010 年至 2021 年期间,在 Koşuyolu 培训与研究医院的超声心动图实验室评估了 16 例诊断为人工瓣膜间歇性故障的患者。
评估的患者包括 12 例双叶二尖瓣置换术和 2 例单叶二尖瓣置换术。间歇性故障的潜在原因分为以下几类:残余腱索(n=4)、阻塞性血栓(n=2)、非阻塞性血栓(n=2)、赘生物(n=2)、瓣叶赘生物和阻塞性血栓共存(n=1)和单纯瓣叶赘生物(n=1)。1 例单叶二尖瓣置换术患者同时存在瓣叶赘生物和阻塞性血栓。另 1 例单叶二尖瓣置换术患者因心律失常导致 12 次心跳中有 1 次出现瓣叶卡滞。还有 2 例主动脉瓣置换术患者。1 例患者因明显钙化导致中度主动脉瓣反流,另 1 例患者因瓣叶赘生物导致中度梗阻。在瓣叶赘生物患者中,1 例患者 6 次心跳中有 1 次出现瓣叶卡滞,1 例患者 2 次心跳中有 1 次出现中度主动脉瓣反流。
间歇性瓣叶卡滞可能导致灾难性后果。在这些患者中做出治疗决策时,评估反流或狭窄程度至关重要。特别是在决定间歇性人工心脏瓣膜功能障碍的最佳治疗方案时,应考虑瓣叶卡滞的频率。