Cuna Alessandra, Pellegrini Francesco, Interlandi Emanuela, Mandarà Erika, De Luca Marco, De Marco Rocco, Ciabattoni Cristina, Zappacosta Antonio, Papayannis Alessandro
Department of Ophthalmology, De Gironcoli Hospital, Conegliano, Italy.
Department of Ophthalmology, Santo Spirito Hospital, Pescara, Italy.
Case Rep Ophthalmol. 2022 Jun 28;13(2):517-522. doi: 10.1159/000525465. eCollection 2022 May-Aug.
A 29-year-old girl presented complaining of acute bilateral visual loss associated with mild headache and retrobulbar pain. She was diagnosed with chiasmal optic neuritis caused by multiple sclerosis. Her visual acuity and visual field defect promptly improved after steroid therapy. However optical coherence tomography angiography showed a progressive reduction of superficial capillary plexus density of the retina and optic nerve consistent with the progressive impairment of the retinal ganglionar cell layer. Contrary to chiasmal compression, in chiasmal optic neuritis, the superficial capillary plexus density reduction is diffuse and does not reflect the peculiar anatomy of the chiasm.
一名29岁女孩前来就诊,主诉双侧急性视力丧失,并伴有轻度头痛和球后疼痛。她被诊断为多发性硬化症引起的视交叉视神经炎。类固醇治疗后,她的视力和视野缺损迅速改善。然而,光学相干断层扫描血管造影显示视网膜和视神经浅表毛细血管丛密度逐渐降低,这与视网膜神经节细胞层的渐进性损伤一致。与视交叉受压不同,在视交叉视神经炎中,浅表毛细血管丛密度降低是弥漫性的,并不反映视交叉的特殊解剖结构。