Chen John J, AbouChehade Jackson E, Iezzi Raymond, Leavitt Jacqueline A, Kardon Randy H
Department of Ophthalmology, Mayo Clinic , Rochester, Minnesota, USA.
Department of Ophthalmology, University of Iowa , Iowa City, Iowa, USA.
Neuroophthalmology. 2017 Jan 27;41(2):76-83. doi: 10.1080/01658107.2016.1275703. eCollection 2017 Apr.
Glaucoma causes a decrease in peripapillary perfused capillary density on optical coherence tomography (OCT) angiography. However, other chronic optic neuropathies have not been explored with OCT angiography to see if these changes were specific to glaucoma. The authors evaluated OCT angiography in 10 patients who suffered various kinds of chronic optic neuropathies, including optic neuritis and ischaemic optic neuropathy, and found that all optic neuropathies showed a decrease in peripapillary vessel density on OCT angiography, regardless of the aetiology of the optic neuropathy. The peripapillary vessel loss on OCT angiography correlated well with the areas of retinal nerve fibre layer thinning seen on OCT.
青光眼会导致光学相干断层扫描(OCT)血管造影显示视乳头周围灌注毛细血管密度降低。然而,尚未通过OCT血管造影对其他慢性视神经病变进行研究,以确定这些变化是否为青光眼所特有。作者对10例患有各种慢性视神经病变(包括视神经炎和缺血性视神经病变)的患者进行了OCT血管造影评估,发现所有视神经病变在OCT血管造影上均显示视乳头周围血管密度降低,无论视神经病变的病因如何。OCT血管造影上视乳头周围血管丢失与OCT上所见的视网膜神经纤维层变薄区域密切相关。