School of Medicine, Debre Markos University, Debre Markos, Ethiopia.
Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Ethiop J Health Sci. 2022 Jul;32(4):755-764. doi: 10.4314/ejhs.v32i4.12.
Non-adherence to prescribed medications is possibly the most common reason for poor treatment outcomes among people with diabetes although its rate is highly variable. Data on the magnitude of medication non-adherence and associated factors are scarce in the study area. This study aimed to assess the rate of non-adherence and associated factors among diabetic patients at Debre Markos Comprehensive Specialized Hospital.
A cross-sectional study was conducted from June 17 to July 17, 2021. Study participants were selected using a simple random sampling technique. Data were collected with a pre-tested structured questionnaire and entered into SPSS version 25. Logistic regression was utilized to determine predictors of medication non-adherence at a significance level of ≤ 0.05.
A total of 176 study participants were enrolled in the study. About 59% of the study participants had type-2 diabetes mellitus. The prevalence of non-adherence to anti-diabetic medications was found to be 41.5%. Male sex, rural residence, being divorced, being merchant, self- or family-borne medical cost, and presence of comorbidities were significantly associated with increased rate of non-adherence to anti-diabetic medications.
The prevalence of non-adherence to medications among diabetic patients is significantly high in the study area. Public health measures should be strengthened to decrease nonadherence among diabetic patients.
尽管糖尿病患者的治疗结局不佳最常见的原因可能是未遵医嘱服药,但这种情况的发生率差异很大。在研究区域,关于药物不依从的程度及其相关因素的数据非常有限。本研究旨在评估德布雷马克罗斯综合专科医院糖尿病患者的不依从率及其相关因素。
本研究于 2021 年 6 月 17 日至 7 月 17 日进行了一项横断面研究。采用简单随机抽样技术选择研究参与者。使用经过预测试的结构化问卷收集数据,并将其输入 SPSS 版本 25。采用逻辑回归来确定药物不依从的预测因素,显著性水平设为≤0.05。
共有 176 名研究参与者被纳入本研究。约 59%的研究参与者患有 2 型糖尿病。抗糖尿病药物不依从的发生率为 41.5%。男性、农村居住、离异、商人、自付或家庭承担医疗费用以及合并症的存在与抗糖尿病药物不依从率的增加显著相关。
在研究区域,糖尿病患者药物不依从的发生率显著较高。应加强公共卫生措施,以降低糖尿病患者的不依从率。