Pharmacology, Neurobiology, Anthropobiology and Environment Laboratory, Department of Biology, Faculty of Sciences Semlalia, Cadi Ayyad University, Marrakech, Morocco.
Endocrinology service, Sidi Mohamed Ben Abdellah hospital, Essaouira, Morocco.
Ethiop J Health Sci. 2022 Jul;32(4):747-754. doi: 10.4314/ejhs.v32i4.11.
Therapeutic observance remains a major problem in managing diabetic subjects, just like in other pathologies treated by medication and lifestyle modification. This study aims to determine the rate of therapeutic observance among diabetic subjects in the province of Essaouira and to identify the factors that influence it.
A cross-sectional questionnaire survey was conducted among 498 type 1 and 2 diabetic subjects, regularly being checked at different health centers in the province of Essaouira (Morocco).
Almost a quarter of the surveyed subjects (23.3%) had poor observance. The results of the binary logistic regression model show that, in order of importance, observance is associated with six factors: Availability and access to medical treatment ( OR: 3; 95% CI confidence interval [1.78-5.03]); the side effects related to the treatment (OR: 2.60; 95% CI [1.65-4.09]); the family support (OR: 1.58 ; 95% CI [0.95-2.61]); duration of diabetes (OR: 0.55 ; 95% CI [0.34-0.88]); the age (OR: 0.50 ; 95% CI [0.30-0.82]); awareness level about the disease (OR: 0.43 ; 95% CI [0.21-0.90]).
The results of the present study have allowed us to identify several factors that can influence therapeutic observance, that prove necessary to be considered and acted upon.
治疗依从性仍然是管理糖尿病患者的主要问题，就像治疗其他需要药物和生活方式改变的疾病一样。本研究旨在确定埃萨乌里亚省糖尿病患者的治疗依从率，并确定影响治疗依从率的因素。
在摩洛哥埃萨乌里亚省的不同卫生中心定期检查的 498 名 1 型和 2 型糖尿病患者中进行了横断面问卷调查。
将近四分之一（23.3%）的被调查患者治疗依从性差。二元逻辑回归模型的结果表明，按重要性顺序，依从性与六个因素相关：医疗可及性和可及性（OR：3；95%置信区间[1.78-5.03]）；与治疗相关的副作用（OR：2.60；95%置信区间[1.65-4.09]）；家庭支持（OR：1.58；95%置信区间[0.95-2.61]）；糖尿病病程（OR：0.55；95%置信区间[0.34-0.88]）；年龄（OR：0.50；95%置信区间[0.30-0.82]）；对疾病的认识水平（OR：0.43；95%置信区间[0.21-0.90]）。
本研究的结果使我们能够确定一些可能影响治疗依从性的因素，这些因素有必要加以考虑和处理。
