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对比自旋回波回波平面成像磁共振弹性成像与梯度回波磁共振弹性成像及其与瞬时弹性成像的相关性。

Comparison of spin-echo echo-planar imaging magnetic resonance elastography with gradient-recalled echo magnetic resonance elastography and their correlation with transient elastography.

机构信息

Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102, Heukseok-ro, Dongjak-gu, Republic of Korea.

Department of Internal Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, 102, Heukseok-ro, Dongjak-gu, Republic of Korea.

出版信息

Diagn Interv Radiol. 2022 Jul;28(4):294-300. doi: 10.5152/dir.2022.201014.

Abstract

PURPOSE This study aimed to assess the agreement between liver stiffness (LS) values obtained by the gradient-recalled echo (GRE) magnetic resonance elastography (MRE) and spin-echo echo-planar imaging (SE-EPI) MRE with those of transient elastography (TE), respectively. METHODS We retrospectively included 48 participants who underwent liver MRE with both GRE and SE-EPI sequences in the same session and also TE within 1 year. We obtained LS values for MRE by drawing free-hand region of interest, and TE was performed using a FibroScan device. We assessed the relationship between the mean LS values obtained by each MRE sequence and TE using the correlation coefficients and Bland-Altman plots, respectively. We also compared LS values and technical failure rates of measured values from MRE between SE-EPI and GRE sequences using the paired t-test and McNemar's test. The MRE failure was defined as the absence of pixel value with a confidence index above 95%. RESULTS The LS values from SE-EPI and GRE sequences strongly correlated with those from TE (GRE; r = 0.73, P < .001 vs. SE-EPI; r = 0.79, P < .001). In addition, the LS values from the 2 MRE sequences showed excellent relationship (intraclass correlation coefficient, 0.94 [0.89-0.97], P < .001). The LS values from SE-EPI and GRE MRE were not significantly different (4.14 kPa vs. 3.88 kPa, P = .19). Furthermore, the technical success rate of SE-EPI MRE was superior to that of GRE (100% vs. 83.8%, P = .031). CONCLUSION The measured LS values obtained using TE correlated strongly with those obtained using GRE and SE-EPI MRE techniques, even though SE-EPI-MRE resulted a higher technical success rate than GRE-MRE. Therefore, we believe that TE, GRE, and SE-EPI MR elastography techniques may complement each other according to the appropriate individual situation.

摘要

目的 本研究旨在评估梯度回波(GRE)磁共振弹性成像(MRE)和自旋回波平面成像(SE-EPI)MRE 与瞬时弹性成像(TE)分别获得的肝硬度(LS)值之间的一致性。

方法 我们回顾性纳入了 48 名在同一次检查中同时接受 GRE 和 SE-EPI 序列肝 MRE 以及在 1 年内接受 TE 的患者。我们通过绘制自由手感兴趣区获得 MRE 的 LS 值,TE 使用 FibroScan 设备进行。我们分别使用相关系数和 Bland-Altman 图评估每个 MRE 序列获得的平均 LS 值与 TE 之间的关系。我们还使用配对 t 检验和 McNemar 检验比较了 SE-EPI 和 GRE 序列 MRE 的 LS 值和测量值的技术失败率。MRE 失败定义为置信指数高于 95%的像素值缺失。

结果 SE-EPI 和 GRE 序列的 LS 值与 TE 非常相关(GRE:r = 0.73,P <.001 与 SE-EPI:r = 0.79,P <.001)。此外,两种 MRE 序列的 LS 值具有良好的相关性(组内相关系数,0.94 [0.89-0.97],P <.001)。SE-EPI 和 GRE MRE 的 LS 值无显著差异(4.14 kPa 与 3.88 kPa,P =.19)。此外,SE-EPI MRE 的技术成功率优于 GRE(100%与 83.8%,P =.031)。

结论 即使 SE-EPI-MRE 比 GRE-MRE 具有更高的技术成功率,使用 TE 获得的测量 LS 值与使用 GRE 和 SE-EPI MRE 技术获得的 LS 值也具有很强的相关性。因此,我们认为根据个体的具体情况,TE、GRE 和 SE-EPI MRE 技术可能相互补充。

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