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白塞病患者感染新型冠状病毒肺炎的临床结局:7例病例系列及文献简要回顾

The Clinical Outcomes of COVID-19 in Patients with Behçet's Disease: A Series of 7 Cases and Brief Review of the Literature.

作者信息

Nas Kemal, Dilek Gamze, Kalçık Unan Mehtap, Tekeoğlu İbrahim, Kamanlı Ayhan

机构信息

Division of Rheumatology and Immunology, Department of Physical Medicine and Rehabilitation, Sakarya University School of Medicine, Sakarya, Turkey.

出版信息

Eurasian J Med. 2022 Oct;54(3):305-309. doi: 10.5152/eurasianjmed.2021.21203.

Abstract

Conventional debates surrounding the treatment of coronavirus disease 2019 still continue in the literature. Colchicine is one of the recommended agents in the treatment of coronavirus disease 2019, but there are also studies giving negative opinions for the said agent. Some researchers suggest that those patients using colchicine have milder clinic symptoms. Behçet's disease is a multisystemic disease with an uncertain etiopathogenesis that is characterized by chronic inflammatory vasculitis. Autoimmunity is believed to play a key role in the pathogenesis of Behçet's disease. Immunomodulator, corticosteroid, and immunosuppressive drugs are used in its treatment. Seven Behçet's patients with coronavirus disease 2019 were presented in this study, and the drugs used, prognosis, accompanying diseases, hospitalization, and complications were discussed in the light of the literature.

摘要

围绕2019冠状病毒病治疗的传统争论在文献中仍在继续。秋水仙碱是治疗2019冠状病毒病的推荐药物之一,但也有研究对该药物给出负面评价。一些研究人员表明,使用秋水仙碱的患者临床症状较轻。白塞病是一种多系统疾病,病因发病机制不明,其特征为慢性炎症性血管炎。自身免疫被认为在白塞病的发病机制中起关键作用。免疫调节剂、皮质类固醇和免疫抑制药物用于其治疗。本研究报告了7例患有2019冠状病毒病的白塞病患者,并根据文献讨论了所使用的药物、预后、伴随疾病、住院情况及并发症。

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本文引用的文献

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Imaging of COVID-19: CT, MRI, and PET.COVID-19 的影像学表现:CT、MRI 和 PET。
Semin Nucl Med. 2021 Jul;51(4):312-320. doi: 10.1053/j.semnuclmed.2020.11.003. Epub 2020 Nov 30.
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COVID-19 and Behçet's disease: clinical case series.新型冠状病毒肺炎与白塞病:临床病例系列
Ann Rheum Dis. 2021 Mar;80(3):e41. doi: 10.1136/annrheumdis-2020-217778. Epub 2020 Jul 21.

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