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患者报告的皮肤癌切除后介入皮瓣修复后的鼻部功能和外观:一项多中心前瞻性队列研究。

Patient-Reported Nasal Function and Appearance After Interpolation Flap Repair Following Skin Cancer Resection: A Multicenter Prospective Cohort Study.

机构信息

Tulane University School of Medicine, New Orleans, Louisiana, USA.

Cooper Medical School of Rowan University, Camden, New Jersey, USA.

出版信息

Facial Plast Surg Aesthet Med. 2023 Mar-Apr;25(2):113-118. doi: 10.1089/fpsam.2021.0271. Epub 2022 Aug 10.

DOI:10.1089/fpsam.2021.0271
PMID:35950993
Abstract

Among patients undergoing two-stage interpolated flap repair of nasal defects, nasal function, and appearance before surgery and at 16 weeks after flap takedown were compared using the Nasal Appearance and Function Evaluation Questionnaire (NAFEQ). Multicenter prospective cohort study. Adult patients with a nasal skin cancer anticipated to require two-stage interpolation flap repair completed the NAFEQ before surgery, at 1 week after flap placement, 4 weeks after flap takedown, and 16 weeks after flap takedown. One hundred sixty-nine patients were enrolled, with 138 patients completing both presurgical and 16-week post-takedown NAFEQs. Overall NAFEQ score increased by 1.09 points (1.91% improvement, confidence interval [95% CI -0.34 to 2.53]). NAFEQ functional subscale increased by 0.72 points (2.58% increase; 95% CI [0.10-1.35]) and appearance subscale increased by 0.37 points (1.28% improvement, 95% CI [-0.65 to 1.39]). At 16 weeks after flap takedown, patients' perceptions of their nasal function and appearance are similar to or slightly improved when compared with their presurgical assessments.

摘要

在接受两阶段插补瓣修复鼻缺损的患者中,使用鼻外观和功能评估问卷(NAFEQ)比较了手术前和瓣取下后 16 周的鼻功能和外观。多中心前瞻性队列研究。预计需要两阶段插值瓣修复的鼻皮肤癌成年患者在手术前、瓣放置后 1 周、瓣取下后 4 周和瓣取下后 16 周完成 NAFEQ。共纳入 169 例患者,其中 138 例患者完成了术前和 16 周瓣取下后 NAFEQ。总体 NAFEQ 评分增加了 1.09 分(1.91%的改善,置信区间[95%CI]-0.34 至 2.53)。NAFEQ 功能子量表增加了 0.72 分(2.58%的增加;95%CI[0.10-1.35]),外观子量表增加了 0.37 分(1.28%的改善,95%CI[-0.65 至 1.39])。瓣取下后 16 周时,与术前评估相比,患者对鼻功能和外观的认知相似或略有改善。

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