Zoetis Inc, Parsippany, NJ, United States of America.
Covetrus, Portland, ME, United States of America.
PLoS One. 2022 Aug 11;17(8):e0271058. doi: 10.1371/journal.pone.0271058. eCollection 2022.
The aim of the current study was to understand how the canine heartworm disease preventive ProHeart® 12 (extended-release injectable moxidectin, PH 12), impacts heartworm preventive purchase compliance and veterinary practice revenue over time compared to monthly heartworm disease preventives. This was a preliminary observational purchase compliance and revenue study based on a retrospective review of transaction data from 4,615 general practices across the United States. The review period was from September 2018 to August 2020. Anonymous transaction records of over 13 million canine patients were analyzed. Of these, only 3.5 million (25.7%) patients purchased any heartworm preventive, as has been presented in other studies. Practices that implemented PH 12 demonstrated the most growth in canine heartworm prevention revenue, patients, and patient compliance levels during the 12-month observation period, compared to previous year. These practices saw year over year growth in percent patients receiving heartworm protection, as well as 10% and 15% growth in the proportion of preventive patients compliant for more than 6 months and 12 months respectively. In contrast, practices that did not bring on PH 12 and only dispensed monthly heartworm preventives saw a decline in the proportion of canine preventive patients that were compliant for more than 6 months. Similarly, PH 12 practices experienced 15% growth in preventive revenue, and practices that did not bring on PH 12 only experienced 3.9% growth in preventive revenue. PH 12 was single-handedly responsible for all growth in patients compliant for more than 6 months in this study. Growth in protection of canine patients with PH 12 proves a helpful tool where mitigation strategies have thus far failed to curb increasing canine heartworm disease prevalence in the US.
本研究旨在了解与每月一次的驱虫预防药物相比,犬心丝虫病预防药物 ProHeart® 12(长效注射型莫昔克丁,PH 12)在一段时间内对犬心丝虫预防药物购买依从性和兽医实践收入的影响。这是一项基于对美国 4615 家普通诊所交易数据的回顾性审查的初步观察性购买依从性和收入研究。审查期为 2018 年 9 月至 2020 年 8 月。对超过 1300 万只犬只的匿名交易记录进行了分析。其中,只有 350 万(25.7%)只犬只购买了任何犬心丝虫预防药物,这在其他研究中也有报道。在 12 个月的观察期内,与前一年相比,实施 PH 12 的诊所犬心丝虫预防收入、患者数量和患者依从性水平增长最快。这些诊所接受心丝虫保护的患者比例逐年增长,超过 6 个月和 12 个月的预防患者比例分别增长了 10%和 15%。相比之下,没有引入 PH 12 而只分发每月一次驱虫预防药物的诊所,超过 6 个月的犬只预防患者的依从比例下降。同样,实施 PH 12 的诊所预防收入增长了 15%,而没有引入 PH 12 的诊所仅增长了 3.9%。在这项研究中,所有超过 6 个月依从性的患者增长都归因于 PH 12。使用 PH 12 保护犬只患者的效果显著,因为迄今为止,减轻策略未能遏制美国犬心丝虫病发病率的上升。