Department of Radiological Sciences, Philadelphia College of Osteopathic Medicine, Moultrie, GA, USA.
Department of Clinical Sciences, Florida State University College of Medicine, Tallahassee, FL, 34239, USA.
Curr Oncol Rep. 2022 Nov;24(11):1461-1475. doi: 10.1007/s11912-022-01319-8. Epub 2022 Aug 12.
To provide an overview of the classifications and clinical hallmarks of common cancer-related conditions that contribute to the high incidence of portal hypertension in this population and provide an update on currently available interventional radiology therapeutic approaches.
In the last few decades, there have been significant advancements in understanding the pathophysiology of portal hypertension. This knowledge has led to the development of safer and more effective minimally invasive approaches. The main objective is to provide alternatives to prevent life-threatening complications from clinically significant portal hypertension and to allow the continuation of cancer treatment interventions that would otherwise be stopped. Clinicians involved in cancer care should be aware of risk factors, associated complications, and management of portal hypertension in cancer patients. Interventional radiology offers minimally invasive alternatives that play a central role in improving clinical outcomes and survival of these patients, allowing the continuation of cancer treatments.
概述常见与癌症相关的病症分类和临床特征,这些病症导致该人群中门静脉高压的高发,并提供目前可用的介入放射学治疗方法的最新信息。
在过去几十年中,人们对门静脉高压的病理生理学有了更深入的了解。这一知识的进步导致了更安全、更有效的微创方法的发展。主要目标是提供替代方案,以预防临床上显著的门静脉高压引起的危及生命的并发症,并允许继续进行否则会停止的癌症治疗干预。参与癌症治疗的临床医生应该了解癌症患者门静脉高压的危险因素、相关并发症和管理。介入放射学提供了微创替代方案,在改善这些患者的临床结果和生存率方面发挥着核心作用,允许继续进行癌症治疗。