Jiménez-Montenegro Lucía, Alfonso Leopoldo, Mendizabal José A, Urrutia Olaia
IS-FOOD Institute, School of Agricultural Engineering and Biosciences, Public University of Navarre (UPNA), Campus de Arrosadia, 31006 Pamplona, Spain.
Animals (Basel). 2022 Jul 27;12(15):1909. doi: 10.3390/ani12151909.
The protein fraction of β-casein may play a key role in the manifestation of a new intolerance: milk protein intolerance. The most common forms of β-casein among dairy cattle breeds are A1 and A2 β-casein. During gastrointestinal digestion of A1 β-casein, an opioid called peptide β-casomorphin-7 (BCM-7) is more frequently released, which can lead to adverse health outcomes. For that reason, novel products labelled as "A2 milk" or "A1-free dairy products" have appeared on the market. In this context, a bibliometric analysis on A2 β-casein research was carried out through the Web of Science (WoS) database. The main objective of this work was to provide an overview of the state of the art in the field of β-casein A2 by analyzing the number of publications per year, trends in thematic content, the most frequently used terms, and the most important institutions and countries in the field. This bibliometric study showed that a greater effort is needed to determine the possible implications of this novel product for human health and the market.
β-酪蛋白的蛋白质部分可能在一种新的不耐受症——牛奶蛋白不耐受症的表现中起关键作用。奶牛品种中最常见的β-酪蛋白形式是A1和A2β-酪蛋白。在A1β-酪蛋白的胃肠道消化过程中，一种名为β-酪蛋白吗啡-7（BCM-7）的阿片样物质更频繁地释放出来，这可能导致不良健康后果。因此，市场上出现了标有“ A2牛奶”或“无A1乳制品”的新型产品。在此背景下，通过科学网（WoS）数据库对A2β-酪蛋白研究进行了文献计量分析。这项工作的主要目的是通过分析每年的出版物数量、主题内容趋势、最常用术语以及该领域最重要的机构和国家，概述A2β-酪蛋白领域的最新技术水平。这项文献计量研究表明，需要做出更大的努力来确定这种新产品对人类健康和市场的可能影响。
