Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul 05029, Republic of Korea.
Department of Biotechnology, Bharathiar University, Coimbatore 641046, Tamil Nadu, India.
Food Chem. 2021 Feb 1;337:127765. doi: 10.1016/j.foodchem.2020.127765. Epub 2020 Aug 5.
β-Casomorphin-7 (BCM-7) is a heptapeptide dietary molecule derived from the digestion of the β-casein of dairy and dairy products. In this review, we have covered the extensive details about BCM and its derived peptides out of the gastrointestinal and enzymatic digestion of milk and milk products, its structure and properties, and its immunological aspects related to human health among infants and adults of both genders. We have left judgment about BCM's pros and cons to the reader by describing the details in a cyclopedic perspective. In addition, a section on the possible ways to detect BCMs from their sources using proteomics, genome-based techniques, such as PCR and aptamers, and other analytical techniques equip the reader to get an idea about the details of the diagnostics available and possible applications in future. Overall, this review will provide information to the end-users of milk and milk products to enable them to make their own decisions about BCMs.
β-酪啡肽-7（BCM-7）是一种七肽膳食分子，来源于乳制品和奶制品中β-酪蛋白的消化。在这篇综述中，我们涵盖了广泛的细节，包括 BCM 及其衍生肽从胃肠道和乳制品消化中产生、其结构和特性、以及它与婴儿和成年男女健康相关的免疫学方面。我们通过从百科全书的角度描述细节，将对 BCM 优缺点的判断留给读者。此外，还有一部分内容介绍了使用蛋白质组学、基于基因组的技术（如 PCR 和适体）以及其他分析技术从其来源中检测 BCM 的可能方法，使读者对现有的诊断细节和未来的可能应用有一个大致的了解。总的来说，这篇综述将为牛奶和奶制品的最终用户提供信息，使他们能够对 BCM 做出自己的决定。
