Khan Anish, Khan Aftab Aslam Parwaz, Marwani Hadi M, Alotaibi Maha Moteb, Asiri Abdullah M, Manikandan Ayyar, Siengchin Suchart, Rangappa Sanjay Mavinkere
Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Polymers (Basel). 2022 Jul 27;14(15):3047. doi: 10.3390/polym14153047.
The development of a sensitive glucose monitoring system is highly important to protect human lives as high blood-glucose level-related diseases continue to rise globally. In this study, a glucose sensor based on polyaniline-bimetallic oxide (PANI-MnBaO) was reported. PANI-MnBaO was electrochemically synthesized on the glassy carbon electrode (GCE) surface. The as-prepared PANI-MnBaO was characterized by field emission scanning electron microscopy, Fourier transform infrared spectroscopy, energy dispersive X-ray spectroscopy, cyclic voltammetry, and electrochemical impedance spectroscopy. Glucose sensing on PANI-MnBaO is based on the electrocatalytic oxidation of glucose to the glucolactone, which gives oxidation current. The oxidation potential for glucose was 0.83 V, with a limit of detection of 0.06 µM in the linear and in the concentration range of 0.05 µM-1.6 mM. The generated current densities displayed excellent stability in terms of repeatability and reproducibility with fast response. The development of a sensitive glucose sensor as obtained in the current study would ensure human health safety and protection through timely and accurate glucose detection and monitoring.
随着全球与高血糖水平相关的疾病持续增加，开发一种灵敏的血糖监测系统对于保护人类生命极为重要。在本研究中，报道了一种基于聚苯胺-双金属氧化物（PANI-MnBaO）的葡萄糖传感器。PANI-MnBaO在玻碳电极（GCE）表面通过电化学方法合成。所制备的PANI-MnBaO通过场发射扫描电子显微镜、傅里叶变换红外光谱、能量色散X射线光谱、循环伏安法和电化学阻抗谱进行表征。PANI-MnBaO上的葡萄糖传感基于葡萄糖电催化氧化为葡萄糖酸内酯，从而产生氧化电流。葡萄糖的氧化电位为0.83 V，在0.05 μM至1.6 mM的线性浓度范围内检测限为0.06 μM。所产生的电流密度在重复性和再现性方面表现出优异的稳定性，响应快速。当前研究中获得的灵敏葡萄糖传感器的开发将通过及时准确的葡萄糖检测和监测确保人类健康安全与保护。
