Jia Huixian, Shang Ningzhao, Feng Yue, Ye Huimin, Zhao Jianing, Wang Huan, Wang Chun, Zhang Yufan
Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Institute of Life Science and Green Development, Hebei University, 071002 Baoding, PR China.
College of Science, Hebei Agricultural University, 071001 Baoding, PR China.
J Colloid Interface Sci. 2021 Feb 1;583:310-320. doi: 10.1016/j.jcis.2020.09.051. Epub 2020 Sep 23.
Transition metal doped carbon materials are recognized as promising sensing platforms for glucose detection. Herein, a simple strategy involving crystallinity, nanostructure engineering, and pyrolysis was developed for constructing well-defined Ni nanoparticle embedded on nanoporous carbon nanorods (Ni/NCNs). A three-dimensional nickel-based metal-organic framework (Ni-MOF) was used as both a self-sacrificing template and precursor. Due to the synergistic effects between the uniformly dispersed Ni nanoparticles and the nanoporous carbon matrix, the as-prepared Ni/NCNs exhibited remarkable electrochemical activity. The fabricated Ni/NCNs glucose sensor showed excellent electrocatalytic performance with ultra-low limit of detection, wide linear detection ranges, fast response times (within 1.6 s), superior stability, and anti-interference characteristics. Moreover, the Ni/NCNs sensing platform was successfully applied to analyze glucose concentrations in human blood samples. These results showed that Ni/NCNs hold potential applications in developing enzyme-free glucose sensors.
过渡金属掺杂的碳材料被认为是用于葡萄糖检测的有前景的传感平台。在此，开发了一种涉及结晶度、纳米结构工程和热解的简单策略，用于构建嵌入纳米多孔碳纳米棒（Ni/NCNs）的明确的镍纳米颗粒。三维镍基金属有机框架（Ni-MOF）用作自牺牲模板和前驱体。由于均匀分散的镍纳米颗粒与纳米多孔碳基质之间的协同效应，所制备的Ni/NCNs表现出显著的电化学活性。所制备的Ni/NCNs葡萄糖传感器具有优异的电催化性能，检测限超低，线性检测范围宽，响应时间快（在1.6秒内），稳定性优异且具有抗干扰特性。此外，Ni/NCNs传感平台成功应用于分析人体血液样本中的葡萄糖浓度。这些结果表明，Ni/NCNs在开发无酶葡萄糖传感器方面具有潜在应用。
