Ravaioli A, Amadori M, Faedi M, Rosti G, Folli S, Barbieri C, Giorgini G, Marangolo M, Emiliani E, Amadori D
Eur J Cancer Clin Oncol. 1986 Dec;22(12):1461-5. doi: 10.1016/0277-5379(86)90080-5.
Primary gastric lymphoma accounts for about 2% of gastric neoplasms. The prognosis of patients affected with non-Hodgkin's gastric lymphoma appears better than for other lymphatic sites. In a retrospective study, the authors have analyzed 45 patients, by evaluating the histopathologic characteristics and relative prognostic factors. The main factors significantly influencing 5-yr survival are: serosal penetration (31.17% vs. 71.2%, P less than 0.05), regional lymph node involvement (53.07% vs. 68%), and clinical stage of disease (IE: 85.6%, IVE:10%, P less than 0.001). The histologic characteristics, the high or low grade of malignancy, and patient age can also be considered important prognostic factors, but not statistically significant in our series of cases. Comparison between overall survival and disease-free survival of patients in stages IE and IIE who underwent surgery alone, with those who had chemotherapy and/or radiotherapy after surgery shows a higher survival (85.6%) of the group who had combined treatments, even though this difference is not statistically significant.
原发性胃淋巴瘤约占胃肿瘤的2%。非霍奇金胃淋巴瘤患者的预后似乎比其他淋巴部位的患者要好。在一项回顾性研究中，作者通过评估组织病理学特征和相关预后因素，分析了45例患者。显著影响5年生存率的主要因素有：浆膜侵犯（31.17%对71.2%，P<0.05）、区域淋巴结受累（53.07%对68%）以及疾病的临床分期（IE期：85.6%，IVE期：10%，P<0.001）。组织学特征、恶性程度的高低以及患者年龄也可被视为重要的预后因素，但在我们的系列病例中无统计学意义。对仅接受手术的IE期和IIE期患者的总生存率和无病生存率，与术后接受化疗和/或放疗的患者进行比较，结果显示联合治疗组的生存率更高（85.6%），尽管这种差异无统计学意义。
