Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China.
Molecules. 2022 Jul 29;27(15):4876. doi: 10.3390/molecules27154876.
Understanding the influence of surfactants on the assembly of peptides has a considerable practical motivation. In this paper, we systematically study the anionic surfactant-assisted assembly of diphenylalanine (FF). FF forms broom-like structures in a concentration of sodium cholate (NaC) around the CMC, and assembles into linear and unidirectional rods in the presence of low and high surfactant concentrations. FF's improved hydrogen bonding and controlled assembly rates are appropriate for other anionic surfactants. At this stage, the use of FF as the simplest protein consequence can be helpful in the investigation of further protein-surfactant interactions.
了解表面活性剂对肽组装的影响具有相当大的实际意义。在本文中，我们系统地研究了二苯丙氨酸（FF）的阴离子表面活性剂辅助组装。FF 在胆酸钠（NaC）的浓度约为 CMC 时形成扫帚状结构，并在低和高表面活性剂浓度下组装成线性和单向棒状。FF 增强的氢键和控制的组装速率适用于其他阴离子表面活性剂。在现阶段，将 FF 用作最简单的蛋白质后果有助于进一步研究蛋白质-表面活性剂相互作用。
