Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Via del Castro Laurenziano 7, 00161 Rome, Italy.
Department of Ingegneria Meccanica ed Aerospaziale, Sapienza University of Rome, Via Eudossiana 18, 00184 Rome, Italy.
Molecules. 2022 Aug 4;27(15):4962. doi: 10.3390/molecules27154962.
(L.) P. Beauv. (couch grass) is a world-wide infesting rhizomatous plant with pharmacological applications. Chemical research is focused on its allelopathic and anti-inflammatory components, which are mainly present in the essential oil. Conversely, the aqueous extracts have been sparingly investigated, although the herbal tea is by far the most used formulation. To fill the gap, the metabolic profile of rhizome herbal tea was investigated by electrospray ionization (ESI) tandem-mass spectrometry (MS/MS); the phenolic profile was investigated by HPLC-PDA-ESI-MS/MS. ESI-MS fingerprinting was provided, evidencing diagnostic ions for saccharides, organic acids and amino acids. The HPLC-PDA-ESI-MS/MS analysis evidenced at least 20 characteristic phenolic compounds, the most representative being caffeoyl and feruloyl quinic esters, followed by coumaric, caffeic and ferulic acids, and hesperidin among flavonoids. In addition, the essential amino acid tryptophan was identified for the first time. The results suggest new perspectives of applications for rhizome.
(L.) P. Beauv.（雀稗）是一种世界性的根茎状植物，具有药理学应用。化学研究集中在其化感和抗炎成分上，这些成分主要存在于精油中。相反，水提取物的研究很少，尽管草药茶是迄今为止使用最广泛的配方。为了填补空白，通过电喷雾电离（ESI）串联质谱（MS/MS）研究了根茎草药茶的代谢谱；通过高效液相色谱-光电二极管阵列-电喷雾质谱/质谱（HPLC-PDA-ESI-MS/MS）研究了酚类谱。提供了 ESI-MS 指纹图谱，为糖、有机酸和氨基酸提供了诊断离子。HPLC-PDA-ESI-MS/MS 分析证实了至少 20 种特征酚类化合物，最具代表性的是咖啡酰和阿魏酰奎宁酸酯，其次是香豆酸、咖啡酸和阿魏酸，以及类黄酮中的橙皮苷。此外，还首次鉴定了必需氨基酸色氨酸。研究结果为根茎的新应用前景提供了依据。
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