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一名患有播散性结核病的青春期女性出现深静脉血栓形成,其蛋白S缺乏:是混杂因素还是存在关联?

Protein S deficiency in an adolescent female with disseminated tuberculosis presenting as deep vein thrombosis: confounder or correlation?

作者信息

Ahmad Najeeb, Chacham Swathi, Singh Avinish, Ppyari Lourembam Radha, Kumar Manish

机构信息

Department of Paediatrics, All India Institute of Medical Sciences, Rishikesh, India.

Department of Paediatrics, All India Institute of Medical Sciences, Gorakhpur, India.

出版信息

Sudan J Paediatr. 2022;22(1):104-108. doi: 10.24911/SJP.106-1583222375.

Abstract

Tuberculosis remains as an infectious disease with a very high prevalence in the Indian subcontinent. Deep vein thrombosis in tuberculosis is due to the increased fibrinogen levels, release of inflammatory cytokines and decreased synthesis of anticoagulant proteins. We present a case of deep venous thrombosis of bilateral lower limbs in association with pulmonary tuberculosis and protein S deficiency.

摘要

结核病在印度次大陆仍然是一种高流行率的传染病。结核病中的深静脉血栓形成是由于纤维蛋白原水平升高、炎性细胞因子释放以及抗凝蛋白合成减少所致。我们报告一例双下肢深静脉血栓形成合并肺结核及蛋白S缺乏的病例。

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本文引用的文献

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Deep venous thrombosis associated with pulmonary tuberculosis and transient protein S deficiency.
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