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与犬类衰老项目中犬只使用关节补充剂相关的人口统计学因素。

Demographic factors associated with joint supplement use in dogs from the Dog Aging Project.

作者信息

Hoffman Jessica M, Tolbert M Katherine, Promislow Daniel E L

机构信息

Department of Biology, University of Alabama at Birmingham, Birmingham, AL, United States.

Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, United States.

出版信息

Front Vet Sci. 2022 Jul 26;9:906521. doi: 10.3389/fvets.2022.906521. eCollection 2022.

Abstract

Osteoarthritis (OA) is one of the most prevalent age-related chronic conditions that afflict companion dogs, and multiple joint supplements are available to prevent or treat OA, though the efficacy of these treatments is controversial. While the demographic factors that are associated with OA diagnosis are well established, the factors that are associated with joint supplement use are not as well studied. Using data collected from the Dog Aging Project, we analyzed owner survey responses regarding joint supplement administration and OA diagnosis for 26,951 adult dogs. In this cross-sectional analysis, logistic regression models and odds-ratios (OR) were employed to determine demographic factors of dogs and their owners that were associated with joint supplement administration. Forty percent of adult dogs in our population were given some type of joint supplement. Perhaps not surprisingly, dogs of older age, larger size, and those that were ever overweight were more likely to receive a joint supplement. Younger owner age, urban living, owner education, and feeding commercial dry food were associated with a reduced likelihood of administration of joint supplements to dogs. Interestingly, mixed breed dogs were also less likely to be administered a joint supplement (OR: 0.73). Dogs with a clinical diagnosis of OA were more likely to receive a joint supplement than those without a reported OA diagnosis (OR: 3.82). Neutered dogs were more likely to have a diagnosis of OA, even after controlling for other demographic factors, yet their prevalence of joint supplement administration was the same as intact dogs. Overall, joint supplement use appears to be high in our large population of dogs in the United States. Prospective studies are needed to determine if joint supplements are more commonly administered as a preventative for OA or after an OA clinical diagnosis.

摘要

骨关节炎(OA)是影响伴侣犬的最常见的与年龄相关的慢性疾病之一,有多种关节补充剂可用于预防或治疗OA,尽管这些治疗方法的疗效存在争议。虽然与OA诊断相关的人口统计学因素已得到充分证实,但与关节补充剂使用相关的因素尚未得到充分研究。利用从犬类衰老项目收集的数据,我们分析了26951只成年犬的主人关于关节补充剂给药和OA诊断的调查回复。在这项横断面分析中,采用逻辑回归模型和比值比(OR)来确定与关节补充剂给药相关的犬及其主人的人口统计学因素。我们研究群体中40%的成年犬接受了某种类型的关节补充剂。也许不足为奇的是,年龄较大、体型较大以及曾经超重的犬更有可能接受关节补充剂。主人年龄较小、居住在城市、主人受过教育以及喂食商业干粮与给犬使用关节补充剂的可能性降低有关。有趣的是,混种犬接受关节补充剂的可能性也较小(OR:0.73)。临床诊断为OA的犬比未报告OA诊断的犬更有可能接受关节补充剂(OR:3.82)。即使在控制了其他人口统计学因素之后,绝育犬被诊断为OA的可能性更大,但其关节补充剂的使用 prevalence与未绝育犬相同。总体而言,在美国我们的大量犬类群体中,关节补充剂的使用似乎很普遍。需要进行前瞻性研究以确定关节补充剂是更常用于预防OA还是在OA临床诊断之后。 (注:原文中“prevalence”翻译为“患病率”更合适,但按照要求未添加解释,此处保留原文错误表述)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e01a/9361857/16377b99d21c/fvets-09-906521-g0001.jpg

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