Padol Monika Vasantrao, Vishwakarma Prashanth, Dodamani Arun Suresh, Gore Anup Wamanrao, Chachlani Karina Shyamlal, Kharkar Shradha Pramod
Department of Public Health Dentistry, A. C. P. M. Dental College, Dhule, Maharashtra, India.
Department of Periodontology, Dr. H. S. R. S. M. Dental College, Dhule, Maharashtra, India.
J Indian Soc Periodontol. 2022 Jul-Aug;26(4):384-389. doi: 10.4103/jisp.jisp_868_20. Epub 2022 Jul 2.
, commonly known as nutmeg, has been shown to have many medicinal properties including reduction of plaque and oral halitosis. In the present study, a mouthwash was prepared from nutmeg oil to compare its effectiveness with 0.2% chlorhexidine (CHX) gluconate mouthwash on halitosis and plaque control.
A total of 60 participants having plaque and plaque-induced oral halitosis were enrolled and randomly divided into two groups as Group A (30) and Group B (30). Nutmeg and 0.2% CHX gluconate mouthwash were administered in Group A and Group B, respectively, for 21 days twice daily. Plaque index and organoleptic score were recorded at baseline, 14 day, and 21 day. The data were collected, tabulated in Microsoft Excel Sheet, and subjected to statistical analysis using appropriate statistical tests.
The percentage of change in plaque score between baseline and 14 day was 12.3% and 9.44% ( = 0.741), between baseline and 21 day 39.2% and 39.4% ( = 0.889), and between 14 and 21 day 27.7% and 29.9% ( = 0.805) for Group A and Group B, respectively, while the percentage of change in halitosis score between baseline and 14 day was 24.7% and 16.3% ( = 0.201), between baseline and 21 day 54.5% and 56.3% ( = 0.487), and between 14 and 21 day 34.9% and 40.0% ( = 0.393) for Group A and Group B, respectively.
Nutmeg mouthwash is organic, economical, and equally effective as compared to 0.2% CHX gluconate mouthwash (Clinical Trials Registry-India/2020/10/028540).
肉豆蔻，俗称肉蔻，已被证明具有多种药用特性，包括减少牙菌斑和口腔口臭。在本研究中，用肉豆蔻油制备了一种漱口水，以比较其与0.2%葡萄糖酸氯己定（CHX）漱口水在口臭和牙菌斑控制方面的效果。
共有60名有牙菌斑和牙菌斑引起的口腔口臭的参与者被纳入研究，并随机分为A组（30人）和B组（30人）。A组和B组分别使用肉豆蔻漱口水和0.2%葡萄糖酸氯己定漱口水，每天两次，共21天。在基线、第14天和第21天记录牙菌斑指数和感官评分。收集数据，整理到Microsoft Excel工作表中，并使用适当的统计测试进行统计分析。
A组和B组在基线至第14天的牙菌斑评分变化百分比分别为12.3%和9.44%（P = 0.741），基线至第21天分别为39.2%和39.4%（P = 0.889），第14天至第21天分别为27.7%和29.9%（P = 0.805）；而在基线至第14天的口臭评分变化百分比分别为24.7%和16.3%（P = 0.201），基线至第21天分别为54.5%和56.3%（P = 0.487），第14天至第21天分别为34.9%和40.0%（P = 0.393）。
肉豆蔻漱口水是有机的、经济的，与0.2%葡萄糖酸氯己定漱口水效果相当（印度临床试验注册中心/2020/10/028540）。
