Beresescu Gabriela, Bereczki-Temistocle Despina Luciana, Beresescu Liana, Ormenisan Alina, Monea Adriana, Razvan-Marius Ion
Faculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540139 Targu Mures, Romania.
Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures, 540139 Targu Mures, Romania.
J Clin Med. 2025 Jul 23;14(15):5225. doi: 10.3390/jcm14155225.
Halitosis is a common condition often rooted in periodontal disease and exacerbated by systemic disorders such as obesity. This short-term clinical evaluation investigates the relationship between halitosis, obesity, and periodontitis, and assesses the efficacy of a natural essential oil mouthwash as an adjunctive oral hygiene intervention. In this randomized, placebo-controlled clinical trial, 45 obese patients with diagnosed periodontitis and self-reported halitosis were randomly assigned to either a test group (n = 30), receiving an essential oil-based mouthwash, or a control group (n = 15), receiving a placebo. Over 28 days, participants were evaluated using plaque index (PI), bleeding on probing (BOP), organoleptic scoring, and BANA test results. Both subjective and objective halitosis assessments were performed. The test group showed marked improvements in all parameters compared to controls. PI decreased by 31.5% in the test group versus 9.25% in controls; BOP reduced by 34.5% versus 6.0%; BANA test positivity dropped by 38.1% in the test group. Organoleptic scores improved by 45.9% (examiner-rated) and 36.8% (self-assessed) in the test group. This 28-day clinical evaluation demonstrates the potential of an essential oil-based mouthwash to significantly reduce halitosis and periodontal inflammation in obese individuals with periodontitis. The necessity of future randomized trials is evident to substantiate the sustained benefits and safety of the intervention.
口臭是一种常见病症,通常源于牙周疾病,并因肥胖等全身性疾病而加重。这项短期临床评估研究了口臭、肥胖与牙周炎之间的关系,并评估了一种天然精油漱口水作为辅助口腔卫生干预措施的效果。在这项随机、安慰剂对照的临床试验中,45名被诊断患有牙周炎且自我报告有口臭的肥胖患者被随机分为试验组(n = 30),使用基于精油的漱口水,或对照组(n = 15),使用安慰剂。在28天的时间里,使用菌斑指数(PI)、探诊出血(BOP)、感官评分和BANA测试结果对参与者进行评估。同时进行了主观和客观的口臭评估。与对照组相比,试验组在所有参数上均有显著改善。试验组的PI下降了31.5%,而对照组下降了9.25%;BOP分别下降了34.5%和6.0%;试验组BANA测试阳性率下降了38.1%。试验组的感官评分(检查者评定)提高了45.9%,(自我评定)提高了36.8%。这项为期28天的临床评估表明,基于精油的漱口水有潜力显著减轻患有牙周炎的肥胖个体的口臭和牙周炎症。显然有必要进行未来的随机试验,以证实该干预措施的持续益处和安全性。