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蜂蜜、葡萄糖酸氯己定(0.2%)以及木糖醇与氯己定漱口水(0.2%)组合对牙菌斑临床水平的比较评估:一项30天的随机对照试验。

Comparative evaluation of honey, chlorhexidine gluconate (0.2%) and combination of xylitol and chlorhexidine mouthwash (0.2%) on the clinical level of dental plaque: A 30 days randomized control trial.

作者信息

Jain Ankita, Bhaskar Dara John, Gupta Devanand, Agali Chandan, Gupta Vipul, Gupta Rajendra Kumar, Yadav Priyanka, Lavate Akash B, Chaturvedi Mudita

机构信息

Department of Public Health Dentistry, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, India.

Department of Public Health Dentistry, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.

出版信息

Perspect Clin Res. 2015 Jan-Mar;6(1):53-7. doi: 10.4103/2229-3485.148819.

Abstract

AIM

To compare the effect of honey, chlorhexidine mouthwash and combination of xylitol chewing gum and chlorhexidine mouthwash on the dental plaque level.

MATERIALS AND METHODS

Ninety healthy dental students, both male and female, aged between 21 to 25 years participated in the study. The subjects were randomly divided into three groups, i.e. the honey group, the chlorhexidine gluconate mouthwash group and the combination of xylitol chewing gum and chlorhexidine (CHX) mouthwash group. The data was collected at the baseline, 15(th) day and 30(th) day; the plaque was disclosed using disclosing solution and their scores were recorded at six sites per tooth using the Quigley and Hein plaque index modified by Turesky-Gilmore-Glickman. Statistical analysis was carried out later to compare the effect of all the three groups. P ≤ 0.05 was considered as statistically significant.

RESULTS

Our result showed that all the three groups were effective in reducing the plaque but post-hoc LSD (Least Significant Difference) showed that honey group and chlorhexidine + xylitol group were more effective than chlorhexidine group alone. The results demonstrated a significant reduction of plaque indices in honey group and chlorhexidine + xylitol group over a period of 15 and 30 days as compared to chlorhexidine.

摘要

目的

比较蜂蜜、洗必泰漱口水以及木糖醇口香糖与洗必泰漱口水联用对牙菌斑水平的影响。

材料与方法

90名年龄在21至25岁之间的健康牙科专业学生(男女均有)参与了本研究。受试者被随机分为三组,即蜂蜜组、葡萄糖酸洗必泰漱口水组以及木糖醇口香糖与洗必泰(CHX)漱口水联用组。在基线、第15天和第30天收集数据;使用菌斑显示剂使菌斑显色,并采用经Turesky-Gilmore-Glickman修改的Quigley和Hein菌斑指数在每颗牙齿的六个部位记录其分数。随后进行统计分析以比较所有三组的效果。P≤0.05被视为具有统计学意义。

结果

我们的结果表明,所有三组在减少菌斑方面均有效,但事后LSD(最小显著差异)显示蜂蜜组和洗必泰+木糖醇组比单独使用洗必泰组更有效。结果表明,与洗必泰相比,蜂蜜组和洗必泰+木糖醇组在15天和30天内菌斑指数显著降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dd5/4314848/cf94f2ea06f9/PCR-6-53-g005.jpg

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