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[14例头颈部结节病分析]

[Analysis of 14 cases of sarcoidosis of head and neck].

作者信息

Zhang Shihan, Meng Xin, Cheng Longlong, Zhang Jingrui, Wang Maiquan, Hou Ming, Lin Dongpeng, Wang Yonggong

机构信息

Henan University People's Hospital;Department of Oral and Maxillofacial Surgery,Henan Provincial People's Hospital,Zhengzhou,450003,China.

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Aug;38(8):721-725. doi: 10.13201/j.issn.2096-7993.2024.08.009.

DOI:10.13201/j.issn.2096-7993.2024.08.009
PMID:39118511
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11612749/
Abstract

To explore the clinical characteristics of sarcoidosis of head and neck symptoms, and to summarize the diagnosis and treatment experience. A retrospective study was conducted on patients with nodular disease with main symptoms in the head and neck who visited Henan Provincial People's Hospital from January 2020 to August 2023. The clinical data including symptom characteristics, pathological characteristics, treatment methods, and prognosis were analyzed. A total of 14 patients were included, with 4 males(28.6%) and 10 females(71.4%), age ranged from 11 to 71 years, with an average age of(52.0±15.8) years. The lesions were located in the parotid gland in 2 cases and the neck in 12 cases. Twelve cases underwent neck mass resection surgery, and 2 cases underwent ultrasound-guided core biopsy of parotid gland tumor and postoperative pathological diagnosis was confirmed in all cases. Four cases received steroid treatment postoperatively, and showed good prognosis with reduced lesion size after 3 months. Three cases did not take medication and the lesions continued to persist, causing discomfort. Seven cases did not take medication postoperatively, and the lesions expanded with multi-organ progression. Patients with head and neck sarcoidosis are rare in clinical practice, and it is prone to misdiagnosis and missed diagnosis. Steroid therapy can achieve good therapeutic effects.

摘要

探讨头颈部结节病的临床特征,总结其诊断及治疗经验。对2020年1月至2023年8月在河南省人民医院就诊的以头颈部为主要症状的结节病患者进行回顾性研究。分析其症状特点、病理特征、治疗方法及预后等临床资料。共纳入14例患者,其中男性4例(28.6%),女性10例(71.4%),年龄11~71岁,平均年龄(52.0±15.8)岁。病变位于腮腺2例,颈部12例。12例行颈部肿块切除术,2例行腮腺肿瘤超声引导下穿刺活检,术后病理诊断均明确。4例术后接受激素治疗,3个月后病变缩小,预后良好。3例未用药,病变持续存在,引起不适。7例术后未用药,病变进展并累及多器官。头颈部结节病临床少见,易误诊、漏诊,激素治疗可取得较好疗效。

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1
[Analysis of 14 cases of sarcoidosis of head and neck].[14例头颈部结节病分析]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2024 Aug;38(8):721-725. doi: 10.13201/j.issn.2096-7993.2024.08.009.
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本文引用的文献

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Cutaneous Sarcoidosis.皮肤结节病。
Dermatol Clin. 2023 Jul;41(3):455-470. doi: 10.1016/j.det.2023.02.012. Epub 2023 Apr 4.
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[Case report of the substantial nasal mass in children and literature review].[儿童鼻腔巨大肿物病例报告及文献复习]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Aug;36(8):636-638. doi: 10.13201/j.issn.2096-7993.2022.08.014.
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Whole genome sequencing identifies variants associated with sarcoidosis in a family with a high prevalence of sarcoidosis.全基因组测序鉴定出一个高发结节病家系中与结节病相关的变异。
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Correction to: BAL biomarkers' panel for differential diagnosis of interstitial lung diseases.对《用于间质性肺疾病鉴别诊断的支气管肺泡灌洗生物标志物面板》的更正
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