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埃及因结核病导致的家庭灾难性总费用:发病率、成本驱动因素及政策影响

Household catastrophic total cost due to tuberculosis in Egypt: incidence, cost drivers and policy implication.

作者信息

Gadallah Mohsen, Amin Wagdy, Rady Mervat

机构信息

Department of Community Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Chest Department, Ministry of Health and Population, Cairo, Egypt.

出版信息

East Mediterr Health J. 2022 Jul 31;28(7):489-497. doi: 10.26719/emhj.22.049.

Abstract

BACKGROUND

Tuberculosis (TB) is a disease that disproportionately affects the poor. The World Health Organization lists economic factors as one of main barriers to tuberculosis management.

AIMS

This study aimed to estimate the household total catastrophic cost of TB and its determinants among newly diagnosed Egyptian tuberculous patients.

METHODS

This was a cohort prospective study covering 257 TB patients registered in 2019. The patients were followed up bi-monthly until the end of the treatment regimen (4 visits). A standardized questionnaire published by the poverty sub-working group of the Stop TB Partnership was used after minor modification. The following costs were measured: pre-diagnosis, direct and indirect, guardian and coping, as well as annual household income. Catastrophic cost (direct plus indirect) was considered if the total cost of TB treatment exceeded 20% of the household's annual income. Sensitivity analyses were conducted using different thresholds.

RESULTS

The incidence of household total catastrophic cost was 24.1%. The mean total cost of TB treatment was US$ 198. Over 50% of the total direct cost was incurred during the pre-diagnosis period. After adjustment for other determinant variables using multivariable logistic regression, we found that age < 30 years, living in a house with crowding index > 2, poverty and coping were more likely to cause higher total catastrophic cost.

CONCLUSIONS

Catastrophic cost was experienced by 1 out of every 4 new TB patients. As the main cost drivers were poverty and coping, the Ministry of Health and Population should be collaborated with Ministry of Finance and NGOs to put a plan of social protection system for poor families with TB patients.

摘要

背景

结核病对贫困人口的影响尤为严重。世界卫生组织将经济因素列为结核病管理的主要障碍之一。

目的

本研究旨在估算埃及新诊断结核病患者家庭的结核病总灾难性成本及其决定因素。

方法

这是一项队列前瞻性研究,涵盖了2019年登记的257例结核病患者。每两个月对患者进行一次随访,直至治疗方案结束(4次访视)。使用了由终止结核病伙伴关系贫困问题工作分组发布的标准化问卷,并稍作修改。测量了以下成本:诊断前成本、直接和间接成本、监护人及应对成本以及家庭年收入。如果结核病治疗总成本超过家庭年收入的20%,则视为灾难性成本(直接成本加间接成本)。使用不同阈值进行敏感性分析。

结果

家庭总灾难性成本发生率为24.1%。结核病治疗的平均总成本为198美元。超过50%的直接总成本发生在诊断前期。在使用多变量逻辑回归对其他决定因素变量进行调整后,我们发现年龄<30岁、居住在拥挤指数>2的房屋中、贫困和应对措施更有可能导致更高的总灾难性成本。

结论

每4名新结核病患者中就有1名经历了灾难性成本。由于主要成本驱动因素是贫困和应对措施,卫生和人口部应与财政部及非政府组织合作,为有结核病患者的贫困家庭制定社会保护系统计划。

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