美国成年人群体重指数、躯干脂肪百分比及全身脂肪百分比与尿失禁之间的关联。
Association between body mass index, trunk and total body fat percentage with urinary incontinence in adult US population.
作者信息
Chen Jiawei, Peng Liao, Xiang Liyuan, Li Boya, Shen Hong, Luo Deyi
机构信息
Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
出版信息
Int Urogynecol J. 2023 May;34(5):1075-1082. doi: 10.1007/s00192-022-05317-z. Epub 2022 Aug 12.
INTRODUCTION AND HYPOTHESIS
To assess the association of body mass index (BMI), trunk and total body fat percentage with the prevalence and severity of urinary incontinence (UI) stratified by gender among a US adult population.
METHODS
A representative cross-sectional survey of participants aged ≥ 20 years was conducted using the data from the 2011-2018 National Health and Nutrition Examination Survey. Multivariate logistic and linear regression models were used to explore the association among the three obesity measures above with the prevalence and severity of UI.
RESULTS
A total of 6964 individuals (4168 males and 2796 females) enrolled for the final analysis. Among males, the weighted prevalence of UI was 7.8%, with 1.3% stress urinary incontinence, 5.8% urge urinary incontinence and 0.7% mixed urinary incontinence. For females, the weighted prevalence of UI was 54.2%, with 31.9% stress urinary incontinence, 7.0% urge urinary incontinence and 15.6% mixed urinary incontinence. Multivariate logistic regression revealed increased BMI and trunk fat percentage significantly increased odds of UI (BMI: OR = 1.05 [per 1 kg/m], 95% CI: 1.03-1.07, P < 0.001; trunk fat percentage: OR = 1.15 [per 5% increase in trunk fat percentage], 95% CI: 1.06-1.25, P = 0.002) in females. Similar trends were observed in the severity of UI (BMI: β = 0.07, 95% CI: 0.05-0.09, P < 0.001; trunk fat percentage: β = 0.18, 95% CI: 0.10-0.26, P < 0.001) by a multivariate linear regression. In males, no significant association was observed (BMI: OR = 0.99 [per 1 kg/m], 95% CI: 0.97-1.02, P = 0.663; trunk fat percentage: OR = 0.95 [per 5% increase in trunk fat percentage], 95% CI: 0.84-1.08, P = 0.430; total fat percentage: OR = 0.94 [per 5% increase in total fat percentage], 95% CI: 0.80-1.10, P = 0.424).
CONCLUSIONS
An increased BMI and trunk fat percentage are significantly associated with higher prevalence and severity of UI in females.
引言与假设
评估美国成年人群中按性别分层的体重指数（BMI）、躯干和全身脂肪百分比与尿失禁（UI）患病率及严重程度之间的关联。
方法
使用2011 - 2018年国家健康与营养检查调查的数据，对年龄≥20岁的参与者进行了一项具有代表性的横断面调查。采用多变量逻辑回归和线性回归模型，探讨上述三种肥胖指标与尿失禁患病率及严重程度之间的关联。
结果
共有6964人（4168名男性和2796名女性）纳入最终分析。在男性中，尿失禁的加权患病率为7.8%，其中压力性尿失禁为1.3%，急迫性尿失禁为5.8%，混合性尿失禁为0.7%。对于女性，尿失禁的加权患病率为54.2%，其中压力性尿失禁为31.9%，急迫性尿失禁为7.0%，混合性尿失禁为15.6%。多变量逻辑回归显示，女性中BMI和躯干脂肪百分比增加显著增加了尿失禁的几率（BMI：比值比[OR]=1.05[每增加1kg/m²]，第95百分位数可信区间[95%CI]：1.03 - 1.07，P<0.001；躯干脂肪百分比：OR = 1.15[躯干脂肪百分比每增加5%]，95%CI：1.06 - 1.25，P = 0.002）。多变量线性回归在尿失禁严重程度方面观察到类似趋势（BMI：β = 0.07，95%CI：0.05 - 0.09，P<0.001；躯干脂肪百分比：β = 0.18，95%CI：0.10 - 0.26，P<0.001）。在男性中，未观察到显著关联（BMI：OR = 0.99[每增加1kg/m²]，95%CI：0.97 - 1.02，P = 0.663；躯干脂肪百分比：OR = 0.95[躯干脂肪百分比每增加5%]，95%CI：0.
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