Department of Urogynaecology, St Mary's Hospital, Imperial College, London, United Kingdom.
Neurourol Urodyn. 2014 Apr;33(4):392-9. doi: 10.1002/nau.22428. Epub 2013 Jun 18.
To evaluate the relationship between body mass index (BMI) and urinary incontinence (UI) in adults ≥40 from the United States, United Kingdom, and Sweden.
This was a secondary analysis of EpiLUTS-a population-representative, cross-sectional, Internet-based survey conducted to assess the prevalence and HRQL impact of urinary symptoms. UI was evaluated by the LUTS Tool and categorized by subgroups: no UI, urgency urinary incontinence (UUI), stress urinary incontinence (SUI), mixed urinary incontinence (MUI) (UUI + SUI), UUI + other UI (OI), SUI + OI, and OI. Descriptive statistics were used. Logistic regressions examined the relationship of BMI to UI controlling for demographics and comorbid conditions.
Response rate was 59%; 10,070 men and 13,178 women were included. Significant differences in BMI were found across UI subgroups. Obesity rates were highest among those with MUI (men and women), SUI + OI (women), UUI and UUI + OI (men). Logistic regressions of each UI subgroup showed that BMI ≥ 30 (obese) was associated with UI in general and MUI (women) and UUI + OI (men). Among women, being obese increased the odds of having SUI and SUI + OI. Women with BMI 25-29.9 (overweight) were more likely to have UI in general and SUI with and without other incontinence (SUI, MUI, and SUI + OI). Being overweight was unrelated to any form of UI in men.
Results were consistent with prior research showing BMI is associated with higher risk of UI. These findings indicate substantial differences in obesity by gender and UI subtype, suggesting different mechanisms for UI other than purely mechanical stress on the bladder.
评估来自美国、英国和瑞典的 40 岁及以上成年人的体重指数（BMI）与尿失禁（UI）之间的关系。
这是对 EpiLUTS 的二次分析，EpiLUTS 是一项基于人群的、横断面的、基于互联网的调查，旨在评估尿症状的患病率和 HRQL 影响。通过 LUTS 工具评估 UI，并按亚组分类：无 UI、急迫性尿失禁（UUI）、压力性尿失禁（SUI）、混合性尿失禁（MUI）（UUI+SUI）、UUI+其他 UI（OI）、SUI+OI 和 OI。采用描述性统计方法。逻辑回归检查了 BMI 与 UI 的关系，控制了人口统计学和合并症。
应答率为 59%；纳入了 10070 名男性和 13178 名女性。在不同的 UI 亚组中，BMI 存在显著差异。在 MUI（男性和女性）、SUI+OI（女性）、UUI 和 UUI+OI（男性）中，肥胖率最高。每个 UI 亚组的逻辑回归显示，BMI≥30（肥胖）与一般 UI 和 MUI（女性）和 UUI+OI（男性）相关。在女性中，肥胖增加了患有 SUI 和 SUI+OI 的几率。BMI 为 25-29.9（超重）的女性更有可能患有一般 UI 和伴有或不伴有其他尿失禁的 SUI（SUI、MUI 和 SUI+OI）。超重与男性的任何形式的 UI 无关。
结果与先前的研究一致，表明 BMI 与更高的 UI 风险相关。这些发现表明，肥胖与性别和 UI 亚型之间存在显著差异，表明 UI 的发生机制不仅与膀胱的机械性压力有关。
