Nagamine C M, Taketo T, Koo G C
Differentiation. 1987;33(3):214-22. doi: 10.1111/j.1432-0436.1987.tb01560.x.
tda-1 XY sex reversal occurs when the Y chromosome of at least some populations of wild Mus musculus domesticus is placed on the C57BL/6J genomic background. Gross anatomical observations have previously revealed morphological similarities among fetal ovotestes of tda-1 and Tas-inherited XY sex reversals and BALB/cWt mosaic hermaphrodites. We studied the histology of tda-1 XY sex-reversed gonads, ranging in age from day 14 of gestation to adult. The obtained data revealed additional similarities with ovotestes of BALB/cWt mosaic hermaphrodites as well as with ovotestes of hermaphrodites found in XXSxr and XX/XY chimeras. It is proposed that ovotestes occurring in these various hermaphroditic conditions may be formed through a common pathway.
当将至少一些野生小家鼠群体的Y染色体置于C57BL/6J基因组背景上时，就会发生tda - 1 XY性反转。大体解剖学观察先前已揭示tda - 1和Tas遗传的XY性反转的胎儿卵睾以及BALB/cWt镶嵌雌雄同体之间的形态学相似性。我们研究了tda - 1 XY性反转性腺的组织学，其年龄范围从妊娠第14天到成年期。获得的数据揭示了与BALB/cWt镶嵌雌雄同体的卵睾以及XXSxr和XX/XY嵌合体中发现的雌雄同体的卵睾的更多相似性。有人提出，在这些不同雌雄同体条件下出现的卵睾可能通过共同途径形成。
