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基于遗传算法的图像重建应用数字全息术与离散正交斯托克威尔变换技术诊断 COVID-19。

Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19.

机构信息

Zonguldak Bülent Ecevit University, Department of Electrical-Electronics Engineering, Zonguldak, 67100, Turkey.

出版信息

Comput Biol Med. 2022 Sep;148:105934. doi: 10.1016/j.compbiomed.2022.105934. Epub 2022 Aug 2.

DOI:10.1016/j.compbiomed.2022.105934
PMID:35961086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9344740/
Abstract

World Health Organization has described the real-time reverse transcription-polymerase chain reaction test method for the diagnosis of the novel coronavirus disease (COVID-19). However, the limited number of test kits, the long-term results of the tests, the high probability of the disease spreading during the test and imaging without focused images necessitate the use of alternative diagnostic methods such as chest X-ray (CXR) imaging. The storage of data obtained for the diagnosis of the disease also poses a major problem. This causes misdiagnosis and delays treatment. In this work, we propose a hybrid 3D reconstruction method of CXR images (CXRI) to detect coronavirus pneumonia and prevent misdiagnosis on CXRI. We used the digital holography technique (DHT) for obtaining a priori information of CXRI stored in created digital hologram (CDH). In this way, the elimination of the storage problem that requires high space was revealed. In addition, Discrete Orthonormal S-Transform (DOST) is applied to the reconstructed CDH image obtained by using DHT. This method is called CDH_DHT_DOST. A multiresolution spatial-frequency representation of the lung images that belong to healthy people and diseased people with the COVID-19 virus is obtained by using the CDH_DHT_DOST. Moreover, the genetic algorithm (GA) is adopted for the reconstruction process for optimization of the CDH image and then DOST is applied. This hybrid method is called CDH_GA_DOST. Finally, we compare the results obtained from CDH_DHT_DOST and CDH_GA_DOST. The results show the feasibility of reconstructing CXRI with CDH_GA_DOST. The proposed method holds promises to meet demands for the detection of the COVID-19 virus.

摘要

世界卫生组织(WHO)已经描述了用于诊断新型冠状病毒病(COVID-19)的实时逆转录-聚合酶链反应检测方法。然而,检测试剂盒数量有限、检测结果需要较长时间、检测过程中疾病传播的可能性较高且影像学检查缺乏聚焦图像,这使得需要使用替代的诊断方法,如胸部 X 射线(CXR)成像。此外,用于诊断疾病的数据存储也存在很大问题,这可能导致误诊和治疗延误。在这项工作中,我们提出了一种 CXR 图像的混合 3D 重建方法(CXRI),用于检测冠状病毒性肺炎并防止 CXRI 误诊。我们使用数字全息技术(DHT)获取存储在创建的数字全息图(CDH)中的 CXRI 的先验信息。这样,就揭示了消除需要高空间存储的问题。此外,离散正交 S-变换(DOST)应用于使用 DHT 获得的重建 CDH 图像。这种方法称为 CDH_DHT_DOST。通过使用 CDH_DHT_DOST,获得了属于健康人和 COVID-19 病毒感染者的肺部图像的多分辨率空间频率表示。此外,采用遗传算法(GA)进行重建过程,以优化 CDH 图像,然后应用 DOST。这种混合方法称为 CDH_GA_DOST。最后,我们比较了 CDH_DHT_DOST 和 CDH_GA_DOST 获得的结果。结果表明,使用 CDH_GA_DOST 重建 CXRI 是可行的。该方法有望满足 COVID-19 病毒检测的需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/907c1978e656/fx1001_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/bc306a373f64/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/9f9cae02b8ee/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/38e8b0f402a0/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/77b9c50ba18b/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/907c1978e656/fx1001_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/bc306a373f64/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/9f9cae02b8ee/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/38e8b0f402a0/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/77b9c50ba18b/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4636/9344740/907c1978e656/fx1001_lrg.jpg

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