van Vliet Erwin A, Immonen Riikka, Prager Ofer, Friedman Alon, Bankstahl Jens P, Wright David K, O'Brien Terence J, Potschka Heidrun, Gröhn Olli, Harris Neil G
Center for Neuroscience, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Amsterdam UMC Location University of Amsterdam, Department of (Neuro)Pathology, Amsterdam Neuroscience, Amsterdam, The Netherlands.
Epilepsia Open. 2022 Aug 13. doi: 10.1002/epi4.12643.
The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs. In this article, we discuss CDEs for neuroimaging data that are collected in rodent models of epilepsy, with a focus on adult rats and mice. We provide detailed CDE tables and case report forms (CRFs), and with this companion manuscript, we discuss the methodologies for several imaging modalities and the parameters that can be collected.
国际抗癫痫联盟/美国癫痫学会（ILAE/AES）联合转化任务组设立了TASK3工作组，以创建临床前癫痫研究各方面的通用数据元素（CDE），这有助于提高实验设计的标准化程度。在本文中，我们讨论了在癫痫啮齿动物模型中收集的神经影像数据的CDE，重点是成年大鼠和小鼠。我们提供了详细的CDE表格和病例报告表（CRF），并在这篇配套论文中讨论了几种成像方式的方法以及可以收集的参数。
