短梗重楼（Brachybotrys paridiformis maxim. Ex oliv.）中的苯丙素类化合物及其抗乙肝病毒活性（II）。

Phenylpropanoids from Brachybotrys paridiformis maxim. Ex oliv. And their anti-HBV activities (II).

作者信息

Wu Si-Tong, Li Fei, Wang Yi-Xiao, Yu Bai-Hong, Ma Chun-Liu, Qiu He-Qin, Wang Guang-Shu

机构信息

School of Pharmaceutical Sciences, Jilin University, Changchun, 130021, People's Republic of China.

School of Science and Technology, Huzhou College, Huzhou, 313000, People's Republic of China.

出版信息

Phytochemistry. 2022 Nov;203:113364. doi: 10.1016/j.phytochem.2022.113364. Epub 2022 Aug 10.

DOI:10.1016/j.phytochem.2022.113364

PMID:35963293

Abstract

Five undescribed phenylpropanoids, one undescribed phenolic glucoside, and sixteen known compounds were isolated from Brachybotrys paridiformis Maxim. Ex Oliv. The undescribed compounds were named brachoside B-C, brach acid A-B, brachnan A, and brachin D, respectively. Additionally, the anti-hepatitis B virus activities of all isolated compounds were studied. Among them, brachnan A, brach acid A, globoidnan A, 3-carboxy-6,7-dihydroxy-1-(3',4'-dihydroxy-phenyl)-naphthalene, and 3,4-dihydroxybenzaldehyde showed significant anti-hepatitis B virus activities.

摘要

从宽叶假排草（Brachybotrys paridiformis Maxim. Ex Oliv.）中分离出了5种未描述的苯丙素类化合物、1种未描述的酚苷和16种已知化合物。这些未描述的化合物分别被命名为假排草苷B - C、假排草酸A - B、假排草萘甲醚A和假排草素D。此外，还研究了所有分离化合物的抗乙型肝炎病毒活性。其中，假排草萘甲醚A、假排草酸A、球花糖芥苷A、3 - 羧基 - 6,7 - 二羟基 - 1 - (3',4' - 二羟基 - 苯基) - 萘和3,4 - 二羟基苯甲醛显示出显著的抗乙型肝炎病毒活性。