八角莲属植物中的苯丙素类成分及其抗乙型肝炎病毒活性。
Phenylpropanoids from Brachybotrys paridiformis Maxim. ex Oliv. and their anti-HBV activities.
机构信息
School of Pharmaceutical Sciences, Jilin University, Changchun, 130021, People's Republic of China.
School of Pharmaceutical Sciences, Jilin University, Changchun, 130021, People's Republic of China.
出版信息
Phytochemistry. 2022 May;197:113114. doi: 10.1016/j.phytochem.2022.113114. Epub 2022 Feb 8.
Using chemical and spectroscopic data, this study on Brachybotrys paridiformis Maxim. ex Oliv. identified four undescribed phenylpropanoids, brachin A-C and brachoside A, together with nine other known compounds. The isolated compounds were tested for anti-hepatitis B virus activities in the HepG2.2.15 cell line. Among them, caffeic anhydride showed the most potent activity.
本研究利用化学和光谱数据鉴定了 Brachybotrys paridiformis Maxim. ex Oliv. 中的四个未描述的苯丙素类化合物，分别为 brachin A-C 和 brachoside A，以及其他九个已知化合物。对分离得到的化合物在 HepG2.2.15 细胞系中进行了抗乙型肝炎病毒活性测试。其中，咖啡酸酐表现出最强的活性。
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