Shaygannejad V, Mirmosayyeb O, Vaheb S, Nehzat N, Ghajarzadeh M
Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Universal Council of Epidemiology (UCE), Universal Scientific Education and Research Network (USERN), Tehran University of Medical Sciences, Tehran, Iran.
Neurologia (Engl Ed). 2025 Jan-Feb;40(1):22-31. doi: 10.1016/j.nrleng.2022.08.002. Epub 2022 Aug 10.
The prevalence of sexual dysfunction (SD) in men with multiple sclerosis (MS) is reported variously in different studies. The most common form of SD in these patients is erectile dysfunction (ED). The goal of this systematic review and meta-analysis is to determine the pooled prevalence of SD and ED in men suffering from MS.
We searched PubMed, Scopus, EMBASE, CINAHL, Web of Science, and gray literature (references of references, and congress abstracts) up to 14th November 2020.
We found 3163 studies by primary search, 2246 were included after deletion of duplicates. Finally, 29 studies were included for meta-analysis. A total of 3349 patients were evaluated. The pooled prevalence of SD was 66% (95% CI: 64%-69%). The pooled prevalence of erectile dysfunction was 49% (95% CI: 47%-50%).
Sexual dysfunction is a prevalent complication of MS in male patients which should be considered by clinicians.
不同研究对多发性硬化症（MS）男性患者性功能障碍（SD）的患病率报道各异。这些患者中最常见的性功能障碍形式是勃起功能障碍（ED）。本系统评价和荟萃分析的目的是确定MS男性患者性功能障碍和勃起功能障碍的合并患病率。
我们检索了截至2020年11月14日的PubMed、Scopus、EMBASE、CINAHL、Web of Science及灰色文献（参考文献的参考文献和会议摘要）。
通过初步检索我们找到3163项研究，删除重复项后纳入2246项。最终，29项研究纳入荟萃分析。共评估了3349例患者。性功能障碍的合并患病率为66%（95%置信区间：64%-69%）。勃起功能障碍的合并患病率为49%（95%置信区间：47%-50%）。
性功能障碍是男性MS患者中一种常见的并发症，临床医生应予以考虑。
