用于高效液相色谱分析的全血中抗炎药物的快速提取。
Rapid extraction of anti-inflammatory drugs in whole blood for HPLC analysis.
作者信息
Moore C M, Tebbett I R
出版信息
Forensic Sci Int. 1987 May-Jun;34(1-2):155-8. doi: 10.1016/0379-0738(87)90093-4.
PMID:3596403
Abstract
A rapid and efficient procedure is described for the extraction and analysis of anti-inflammatory drugs in whole blood. Red blood cells were fragmented by sonication and the blood sample extracted by passing through a bonded silica column (Bond-Elut). The adsorbed drugs were washed and eluted followed by analysis by HPLC. Recoveries were in excess of 80% at 5 micrograms/ml concentrations.
摘要
本文描述了一种快速高效的全血中抗炎药物提取和分析方法。通过超声破碎红细胞，血液样本通过键合硅胶柱（Bond-Elut）进行提取。吸附的药物经洗涤和洗脱后，采用高效液相色谱法进行分析。在5微克/毫升浓度下，回收率超过80%。
Zotero 插件