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墨西哥痴呆症及主要亚型的流行率:墨西哥老龄化与痴呆症研究(SADEM)。

Prevalence of Dementia and Main Subtypes in Mexico: The Study on Aging and Dementia in Mexico (SADEM).

机构信息

Unidad de Investigación Epidemiológica y en Servicios de Salud, Área de Envejecimiento, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Unidad de Investigación en Epidemiología Clínica, Hospital General Regional No 1 Carlos Mcgregor Sánchez Navarro, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

出版信息

J Alzheimers Dis. 2022;89(3):931-941. doi: 10.3233/JAD-220012.

Abstract

BACKGROUND

Dementia is a priority public health issue due to its high prevalence worldwide and its economic, social, and health impact. However, there are few reports in Mexico based on formal tests and with a clinical approach based on the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5).

OBJECTIVE

This study estimates the prevalence of the main types of dementia among elderly people living in the community in Mexico City.

METHODS

A population-based, two-step study was conducted, including 6,204 elderly individuals aged 60 or above with in-home assessment. All participants were screened for cognitive impairment; those who presented some cognitive problem underwent a standardized neurological examination. Each diagnosis was based on the criteria for dementia in the DSM-5, and the final consensus diagnosis of dementia was determined by an expert panel.

RESULTS

The global estimated prevalence of dementia in the Mexican population was 7.8% met the criteria for Alzheimer's disease, 4.3% for vascular dementia, and 2.1% for mixed dementia. The prevalence of dementia was higher in women than in men (15.3% versus 12.5%, respectively).

CONCLUSION

These results provide evidence to propose strategies for Latin American countries where dementia represents a challenge due to the heterogeneity of the populations and socioeconomic disparities, requiring early diagnosis and at the first levels of care.

摘要

背景

由于痴呆症在全球的高患病率及其对经济、社会和健康的影响,它已成为一个优先的公共卫生问题。然而,墨西哥基于正式测试和基于精神障碍诊断与统计手册,第五版(DSM-5)的临床方法的报告很少。

目的

本研究估计了墨西哥城社区中老年人中主要类型痴呆的患病率。

方法

进行了一项基于人群的两步研究,包括 6204 名 60 岁及以上的在家中接受评估的老年人。所有参与者都接受了认知障碍的筛查;那些出现一些认知问题的人接受了标准化的神经学检查。每个诊断都基于 DSM-5 中的痴呆标准,痴呆的最终共识诊断由专家小组确定。

结果

全球估计的墨西哥人口中痴呆症的患病率为 7.8%符合阿尔茨海默病的标准,4.3%符合血管性痴呆的标准,2.1%符合混合性痴呆的标准。女性的痴呆症患病率高于男性(分别为 15.3%和 12.5%)。

结论

这些结果为拉丁美洲国家提供了证据,这些国家由于人口和社会经济差异的异质性,痴呆症构成了挑战,需要早期诊断和初级保健。

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