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印度喀拉拉邦一个农村社区痴呆症的流行病学研究。

An epidemiological study of dementia in a rural community in Kerala, India.

作者信息

Shaji S, Promodu K, Abraham T, Roy K J, Verghese A

机构信息

N. V. P. Medical Centre, Thevanal Valley, Kerala, India.

出版信息

Br J Psychiatry. 1996 Jun;168(6):745-9. doi: 10.1192/bjp.168.6.745.

DOI:10.1192/bjp.168.6.745
PMID:8773818
Abstract

BACKGROUND

This community-based epidemiologic study of dementia in a rural population in India investigated the prevalence of various dementing disorders in the community, psychosocial correlates of the morbidity, and assessment of the risk factors associated with dementia.

METHOD

A door to door survey was conducted to identify elderly people aged 60 and above. A total of 2067 elderly persons were then screened with a vernacular adaptation of the MMSE. All those who scored 23 and below had a detailed neuropsychological evaluation by CAMDEX-Section B, and the care-givers of the people with confirmed cognitive impairment were interviewed using CAMDEX-Section H to confirm the history of deterioration or impairment in social or personal functioning. In the third phase the subjects with confirmed cognitive impairment were evaluated at home as to whether they satisfied the DSM-III-R criteria for dementia. Subcategorisation of dementia was done based on ICD-10 diagnostic criteria. Five percent of those whose screening was negative were randomly selected and evaluated during each stage.

RESULTS

Sixty-six cases of dementia were identified from 2067 persons aged 60 and above, a prevalence rate of 31.9 per thousand. After correction this rate was 33.9 per thousand. Fifty-eight percent of the dementia cases were diagnosed as vascular dementia and 41% satisfied the criteria for ICD-10 dementia in Alzheimer's disease. There were more women in the Alzheimer's disease group; smoking and hypertension were associated with vascular dementia while a family history of dementia was more likely in the Alzheimer's group.

CONCLUSION

Dementia is an important cause of morbidity in the geriatric population in this community, where families take responsibility for the care of relatives with dementia.

摘要

背景

这项针对印度农村人口痴呆症的社区流行病学研究调查了社区中各种痴呆症的患病率、发病率的社会心理相关因素以及与痴呆症相关的风险因素评估。

方法

进行挨家挨户的调查以识别60岁及以上的老年人。然后用MMSE的当地语言改编版对总共2067名老年人进行筛查。所有得分23分及以下的人都通过CAMDEX - B部分进行了详细的神经心理学评估,并且使用CAMDEX - H部分对确诊为认知障碍者的照料者进行访谈,以确认社会或个人功能恶化或受损的病史。在第三阶段,对确诊为认知障碍的受试者在家中评估其是否符合DSM - III - R痴呆症标准。根据ICD - 10诊断标准对痴呆症进行亚分类。在每个阶段随机选择5%筛查阴性的人进行评估。

结果

从2067名60岁及以上的人中识别出66例痴呆症患者,患病率为千分之31.9。校正后该率为千分之33.9。58%的痴呆症病例被诊断为血管性痴呆,41%符合ICD - 10阿尔茨海默病痴呆症标准。阿尔茨海默病组女性更多;吸烟和高血压与血管性痴呆相关,而痴呆症家族史在阿尔茨海默病组更常见。

结论

在这个社区的老年人群中,痴呆症是发病的一个重要原因,在该社区家庭负责照料患有痴呆症的亲属。

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