Briller Joan E, Aggarwal Niti R, Davis Melinda B, Hameed Afshan B, Malhamé Isabelle, Mahmoud Zainab, McDonald Emily G, Moraes de Oliveira Glaucia, Quesada Odayme, Scott Nandita S, Sharma Jyoti
Division of Cardiology, Department of Medicine and Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, Illinois, USA.
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.
JACC Adv. 2022 Aug;1(3):100057. doi: 10.1016/j.jacadv.2022.100057. Epub 2022 Aug 10.
Cardiovascular complications are frequently present in coronavirus-2019 (COVID-19) infection. These include microvascular and macrovascular thrombotic complications such as arterial and venous thromboembolism, myocardial injury or inflammation resulting in infarction, heart failure, and arrhythmias. Data suggest increased risk of adverse outcomes in pregnant compared with nonpregnant women of reproductive age with COVID-19 infection, including need for intensive care unit admission, mechanical ventilation, and extracorporeal membrane oxygenation utilization. Current statements addressing COVID-19-associated cardiac complications do not include pregnancy complications that may mimic COVID-19 complications such as peripartum cardiomyopathy, spontaneous coronary artery dissection, and preeclampsia. Unique to pregnancy, COVID-19 complications can result in preterm delivery and modify management of the pregnancy. Moreover, pregnancy has often been an exclusion criterion for enrollment in research studies. In this review, we summarize what is known about pregnancy-associated COVID-19 cardiovascular complications.
心血管并发症在2019冠状病毒病（COVID-19）感染中很常见。这些并发症包括微血管和大血管血栓形成并发症，如动脉和静脉血栓栓塞、导致梗死的心肌损伤或炎症、心力衰竭和心律失常。数据表明，与感染COVID-19的非妊娠育龄妇女相比，孕妇出现不良结局的风险增加，包括入住重症监护病房、机械通气和使用体外膜肺氧合的需求。目前关于COVID-19相关心脏并发症的声明未包括可能模仿COVID-19并发症的妊娠并发症，如围产期心肌病、自发性冠状动脉夹层和子痫前期。COVID-19并发症在妊娠中具有独特性，可导致早产并改变妊娠管理。此外，妊娠常常是研究纳入的排除标准。在本综述中，我们总结了已知的与妊娠相关的COVID-19心血管并发症。
