Yadavalli Krishna, Lepore Salvatore D
Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, Florida 33431, USA.
Lett Org Chem. 2022 Aug;19(8):597-601. doi: 10.2174/1570178619666211231113033. Epub 2022 Feb 1.
Chiral allenylcarbonyls such as allenoates remain underutilized in complex synthesis despite recent advances in synthesis methods to prepare them non-racemically. The field is now ripe for the employment of this class of allenes as building blocks to facilitate the construction of complex small-molecule compounds, such as bridged bicycles.
尽管最近在制备非外消旋手性联烯基羰基化合物（如联烯酸酯）的合成方法上取得了进展，但它们在复杂合成中的应用仍然不足。现在，将这类联烯用作构建单元以促进复杂小分子化合物（如桥环双环化合物）的构建的时机已经成熟。
