Astrup Jens, Gyntelberg Finn
Department of Neurology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
Front Neurol. 2022 Jul 29;13:912348. doi: 10.3389/fneur.2022.912348. eCollection 2022.
The natural history and clinical course of tension-type headache and non-specific low back pain are reconsidered. By closer examination, these two conditions appear to share several specific clinical features. Both are muscular pain conditions along the spine, they have a preponderance in women, they may occur spontaneously or follow a trivial traumatic incident, and they both have a high risk of chronicity. The affected muscles are tender with tender points. EMG indicates diffuse hyperactivity and abnormal activation pattern, and motor control of the affected muscles and adjacent muscle groups is discoordinated. These shared features suggest analogous pathophysiology involving the neuromotor control of affected and adjacent muscle groups in the cervical and lumbar regions, respectively. As recently suggested for the whiplash disease, we suggest the term spinal dyssynergia for this specific pattern of pathology. This suggestion provides a new perspective for the understanding of these diseases by placing their cause within the central nervous system and not in the spine or spinal musculature. This perspective warrants further clinical, neurophysiological, and neuropharmacological studies of this 'family' of common yet poorly understood clinical muscular pain conditions along the spine.
紧张型头痛和非特异性下腰痛的自然病史和临床病程被重新审视。通过更仔细的检查,这两种情况似乎有几个特定的临床特征。两者都是脊柱沿线的肌肉疼痛病症,在女性中更为常见,它们可能自发出现或继发于轻微的创伤事件,并且它们都有很高的慢性化风险。受影响的肌肉有压痛点且触痛。肌电图显示弥漫性活动亢进和异常激活模式,并且受影响肌肉和相邻肌肉群的运动控制不协调。这些共同特征表明存在类似的病理生理学,分别涉及颈部和腰部区域受影响及相邻肌肉群的神经运动控制。正如最近对挥鞭样损伤疾病所提出的那样,我们建议将这种特定的病理模式称为脊柱协同失调。这一建议通过将这些疾病的病因置于中枢神经系统而非脊柱或脊柱肌肉组织中,为理解这些疾病提供了一个新的视角。这一视角值得对这一常见但了解不足的脊柱沿线临床肌肉疼痛病症“家族”进行进一步的临床、神经生理学和神经药理学研究。