Department of Gynaecology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
China Academy of Chinese Medical Sciences, Beijing, China.
Front Public Health. 2022 Jul 28;10:960965. doi: 10.3389/fpubh.2022.960965. eCollection 2022.
Polycystic ovary syndrome (PCOS) is a common clinical disease often associated with insulin resistance (IR). The interaction between PCOS and IR will promote the progress of PCOS and the risk of related complications, harm women's physical and mental health, and increase the social and economic burden.
PCOS IR-related works of literature were retrieved through the Web of Science Core Collection (WoSCC) Database and imported into VOSviewer and CiteSpace, respectively, in plain text format to conduct the literature visualization analysis of authors, countries, institutions, highly cited works of literature, and keywords, aiming to reveal the hot spots and trends of PCOS IR fields.
A total of 7,244 articles were retrieved from 1900 to 2022. Among them, the United States has made the largest contribution. Diamanti-Kandarakis E was the author with the most publications, and the University of Athens was the institution with most publications. Keyword analysis showed that PCOS interacts with IR mainly through sex-hormone binding globulin, luteinizing hormone, insulin-like growth factor, oxidative stress, and other mechanisms. In addition, the complications of PCOS complicated with IR are also the focus of researchers' attention.
Through bibliometric analysis, this paper obtains the research hotspot and trend of PCOS IR fields, which can provide a reference for subsequent research.
多囊卵巢综合征（PCOS）是一种常见的临床疾病，常伴有胰岛素抵抗（IR）。PCOS 和 IR 的相互作用会促进 PCOS 的进展和相关并发症的风险，危害女性身心健康，增加社会和经济负担。
通过 Web of Science Core Collection（WoSCC）数据库检索 PCOS IR 相关文献，并以纯文本格式分别导入 VOSviewer 和 CiteSpace 进行文献可视化分析，包括作者、国家/地区、机构、高被引文献和关键词，旨在揭示 PCOS IR 领域的热点和趋势。
共检索到 1900 年至 2022 年的 7244 篇文章。其中，美国的贡献最大。Diamanti-Kandarakis E 是发表文献最多的作者，而雅典大学则是发表文献最多的机构。关键词分析表明，PCOS 与 IR 主要通过性激素结合球蛋白、黄体生成素、胰岛素样生长因子、氧化应激等机制相互作用。此外，PCOS 合并 IR 的并发症也是研究人员关注的焦点。
通过文献计量分析，本文获得了 PCOS IR 领域的研究热点和趋势，可为后续研究提供参考。
