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实验室大鼠和小鼠在暴露于分散的中子激活 56Mn 粉末时的外照射剂量估计。

External dose estimates of laboratory rats and mice during exposure to dispersed neutron-activated 56Mn powder.

机构信息

A. Tsyb Medical Radiological Research Center - Branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Koroleva Str., 4., Obninsk, Kaluga Region 2490036, Russian Federation.

Ibaraki Prefectural University of Health Sciences, 4669-2, Ami-machi, Inashiki-gun, Ibaraki 300-0394, Japan.

出版信息

J Radiat Res. 2022 Aug 13;63(Supplement_1):i16-i20. doi: 10.1093/jrr/rrac032.

Abstract

Estimates of external absorbed dose in experimental animals exposed to sprayed neutron-activated 56Mn powder are necessary for comparison with internal absorbed doses estimated under the same exposure conditions, which is required for a correct interpretation of the observed biological effects. It has been established that the measured dose of external absorbed dose as a result of gamma irradiation range 1-15 mGy, which is order of magnitude less than the maximal dose of internal gamma and beta irradiation of the whole body of the same experimental animals irradiated under the same conditions: according to the available literature data, the maximal values ​​of absorbed dose of internal gamma-beta irradiation of the whole body are in the range of 330 mGy-1200 mGy for mice and 100 mGy-150 mGy for rats. It is concluded that under the conditions of experiments with dispersed neutron-activated powder 56MnO2, internal gamma-beta irradiation of experimental animals is the main factor of radiation exposure compared to external gamma irradiation.

摘要

估算暴露于喷雾式中子激活 56Mn 粉末的实验动物的外照射吸收剂量,对于与相同暴露条件下估算的内照射吸收剂量进行比较是必要的,这是正确解释所观察到的生物效应所必需的。已经确定,由于伽马辐射范围为 1-15 mGy,测量到的外照射吸收剂量仅为相同实验动物在相同条件下全身内照射的伽马和β辐射最大剂量的数量级:根据现有文献数据,全身内γ-β辐射吸收剂量的最大值在范围为 330 mGy-1200 mGy 之间,对于小鼠,而对于大鼠,则为 100 mGy-150 mGy。因此,可以得出结论,与外照射伽马辐射相比,在分散式中子激活 56MnO2 粉末的实验条件下,实验动物的内γ-β辐射是辐射暴露的主要因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e21/9377039/c56783a7ee0e/rrac032f1.jpg

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