Tarter R E, Hegedus A M, Van Thiel D H, Edwards N, Schade R R
Int J Neurosci. 1987 Feb;32(3-4):901-10. doi: 10.3109/00207458709043346.
Subjects with three different types of hepatic cirrhosis were compared on a battery of neuropsychological tests to determine if cerebral dysfunction varied according to the type of liver disease. It was found that the manifest cognitive impairments varied according to the type and etiology of the liver disease. These findings underscore the sensitivity of neuropsychological tests in the detection of hepatic encephalopathy, particularly in cases where there are no overt clinical signs or symptoms of neurologic disturbance. They also suggest that the nature and severity of the measurable neuropsychological abnormalities may vary within patient populations depending upon the etiology of the individual's liver disease and the specific pathophysiological mechanisms involved in its progression.
对患有三种不同类型肝硬化的受试者进行了一系列神经心理学测试，以确定脑功能障碍是否因肝病类型而异。结果发现，明显的认知障碍因肝病的类型和病因而异。这些发现强调了神经心理学测试在检测肝性脑病方面的敏感性，特别是在没有明显神经功能障碍临床体征或症状的情况下。它们还表明，可测量的神经心理异常的性质和严重程度在患者群体中可能因个体肝病的病因及其进展中涉及的特定病理生理机制而异。
