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瑞典北部社会人口因素与结直肠癌诊断时间的相关性。

The association between sociodemographic factors and time to diagnosis for colorectal cancer in northern Sweden.

机构信息

Department of Nursing, Umeå University, Umeå, Sweden.

Department of Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Sweden.

出版信息

Eur J Cancer Care (Engl). 2022 Nov;31(6):e13687. doi: 10.1111/ecc.13687. Epub 2022 Aug 15.

DOI:10.1111/ecc.13687
PMID:35970596
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9787547/
Abstract

OBJECTIVES

This study examined whether sociodemographic factors, including distance to hospital, were associated with differences in the diagnostic interval and the treatment interval for colorectal cancer in northern Sweden.

METHODS

Data were retrieved from the Swedish cancer register on patients (n = 446) diagnosed in three northern regions during 2017-2018, then linked to data from Statistics Sweden and medical records. Also, Google maps was used to map the distance between patients' place of residence and nearest hospital. The different time intervals were analysed using Mann-Whitney U-test and Cox regression.

RESULTS

Differences in time to diagnosis were found between groups for income and distance to hospital, favouring those with higher income and shorter distance. The unadjusted regression analysis showed higher income to be associated with more rapid diagnosis (HR 1.004, CI 1.001-1.007). This association remained in the fully adjusted model for income (HR 1.004, CI 1.000-1.008), but not for distance. No differences between sociodemographic groups were found in the treatment interval.

CONCLUSION

Higher income and shorter distance to hospital were in the unadjusted models associated with shorter time to diagnosis for patients with CRC in northern Sweden. The association remained for income when adjusting for other variables even though the difference was small.

摘要

目的

本研究旨在探讨在瑞典北部,社会人口因素(包括到医院的距离)是否与结直肠癌的诊断间隔和治疗间隔存在差异有关。

方法

从 2017 年至 2018 年在瑞典北部三个地区诊断的患者的瑞典癌症登记处获取数据(n=446),然后与瑞典统计局和医疗记录的数据进行关联。还使用谷歌地图绘制了患者居住地和最近医院之间的距离。使用 Mann-Whitney U 检验和 Cox 回归分析了不同的时间间隔。

结果

在收入和到医院的距离方面,不同组之间的诊断时间存在差异,收入较高和距离较短的患者具有优势。未调整的回归分析显示,较高的收入与更快速的诊断相关(HR 1.004,CI 1.001-1.007)。这种关联在收入的完全调整模型中仍然存在(HR 1.004,CI 1.000-1.008),但对于距离则不然。在治疗间隔方面,社会人口群体之间没有差异。

结论

在未调整模型中,较高的收入和较短的到医院距离与瑞典北部 CRC 患者的诊断时间较短有关。在调整其他变量后,收入的相关性仍然存在,尽管差异较小。

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本文引用的文献

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BMC Cancer. 2021 Jun 30;21(1):757. doi: 10.1186/s12885-021-08415-1.
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The effectiveness of the colorectal cancer referral pathway - identification of colorectal cancer in a Swedish region.
结直肠癌转诊途径的效果——瑞典某地区结直肠癌的检出率。
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Socio-demographic variation in stage at diagnosis of breast, bladder, colon, endometrial, lung, melanoma, prostate, rectal, renal and ovarian cancer in England and its population impact.英国各年龄段人群乳腺癌、膀胱癌、结肠癌、子宫内膜癌、肺癌、黑色素瘤、前列腺癌、直肠癌、肾癌和卵巢癌诊断时的社会人口学差异及其对人群的影响。
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